Emerging antibody-based therapeutics against SARS-CoV-2 during the global pandemic

Y Sun, M Ho - Antibody therapeutics, 2020 - academic.oup.com
SARS-CoV-2 antibody therapeutics are being evaluated in clinical and preclinical stages. As
of 11 October 2020, 13 human monoclonal antibodies targeting the SARS-CoV-2 spike …

SARS-CoV-2 neutralizing antibodies for COVID-19 prevention and treatment

D Li, GD Sempowski, KO Saunders… - Annual review of …, 2022 - annualreviews.org
Prophylactic and therapeutic drugs are urgently needed to combat coronavirus disease
2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV …

COVID-19 antibody therapeutics tracker: a global online database of antibody therapeutics for the prevention and treatment of COVID-19

L Yang, W Liu, X Yu, M Wu, JM Reichert… - Antibody …, 2020 - academic.oup.com
Facing the COVID-19 global healthcare crisis, scientists worldwide are collaborating to
develop prophylactic and therapeutic interventions against the disease. Antibody …

Neutralizing antibodies against SARS-CoV-2: current understanding, challenge and perspective

Y Huang, H Sun, H Yu, S Li, Q Zheng… - Antibody …, 2020 - academic.oup.com
The rapid emergence of Coronavirus disease-2019 (COVID-19) caused by severe acute
respiratory syndrome 2 coronavirus (SARS-CoV-2) as a pandemic that presents an urgent …

Preclinical characterization of amubarvimab and romlusevimab, a pair of non-competing neutralizing monoclonal antibody cocktail, against SARS-CoV-2

Y Ji, Q Zhang, L Cheng, J Ge, R Wang, M Fang… - Frontiers in …, 2022 - frontiersin.org
Monoclonal antibodies (mAbs) targeting the severe acute respiratory syndrome coronavirus
2 (SARS-CoV-2) spike protein have demonstrated clinical efficacy in preventing or treating …

Broad strategies for neutralizing SARS-CoV-2 and other human coronaviruses with monoclonal antibodies

Z Ling, C Yi, X Sun, Z Yang, B Sun - Science China Life Sciences, 2023 - Springer
Antibody therapeutics and vaccines for coronavirus disease 2019 (COVID-19) have been
approved in many countries, with most being developed based on the original strain of …

The neutralizing antibody, LY-CoV555, protects against SARS-CoV-2 infection in nonhuman primates

BE Jones, PL Brown-Augsburger, KS Corbett… - Science translational …, 2021 - science.org
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) poses a public health
threat for which preventive and therapeutic agents are urgently needed. Neutralizing …

[PDF][PDF] Potent neutralization of SARS-CoV-2 in vitro and in an animal model by a human monoclonal antibody

W Li, A Drelich, DR Martinez, L Gralinski, C Chen… - BioRxiv, 2020 - researchgate.net
Effective therapies are urgently needed for the SARS-CoV-2/COVID19 pandemic. We
identified panels of fully human monoclonal antibodies (mAbs) from eight large …

[PDF][PDF] LY-CoV1404 (bebtelovimab) potently neutralizes SARS-CoV-2 variants

K Westendorf, S Žentelis, L Wang, D Foster… - Cell reports, 2022 - cell.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-neutralizing monoclonal
antibodies (mAbs) can reduce the risk of hospitalization from coronavirus disease 2019 …

Development and structural basis of a two-MAb cocktail for treating SARS-CoV-2 infections

C Zhang, Y Wang, Y Zhu, C Liu, C Gu, S Xu… - Nature …, 2021 - nature.com
The ongoing pandemic of coronavirus disease 2019 (COVID-19) is caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2). Neutralizing antibodies against SARS …