An initial dosing method for teicoplanin based on the area under the serum concentration time curve required for MRSA eradication

N Kanazawa, K Matsumoto, T Fukamizu… - Journal of Infection and …, 2011 - Elsevier
Teicoplanin is a glycopeptide antibacterial agent that has a long serum half-life and
therefore takes time to achieve steady-state conditions. An appropriate initial dosing is …

Determination of teicoplanin trough concentration target and appropriate total dose during the first 3 days: a retrospective study in patients with MRSA infections

K Matsumoto, N Kanazawa, T Fukamizu… - Journal of infection and …, 2010 - Elsevier
An initial loading procedure has been recommended to enable teicoplanin to promptly reach
an effective serum concentration for the treatment of methicillin-resistant Staphylococcus …

Recommended initial loading dose of teicoplanin, established by therapeutic drug monitoring, and outcome in terms of optimal trough level

M Sato, K Chida, T Suda, H Gemma… - Journal of infection and …, 2006 - Elsevier
Teicoplanin has a long serum half-life, and therefore it takes time to reach a steady-state
concentration. An initial loading procedure has been recommended for teicoplanin to enable …

Pharmacokinetic/pharmacodynamic analysis of teicoplanin in patients with MRSA infections

K Matsumoto, E Watanabe, N Kanazawa… - Clinical …, 2016 - Taylor & Francis
Background Teicoplanin is a glycopeptide antibiotic that has been used to treat serious,
invasive infections caused by Gram-positive bacteria. The area under the drug concentration …

Impact of teicoplanin maintenance dose and MIC values on the clinical outcomes of patients treated for methicillin-resistant Staphylococcus aureus bacteremia

CY Tsai, CH Lee, CC Chien, IL Chen - Infection and Drug …, 2018 - Taylor & Francis
Objectives: Teicoplanin, a glycopeptide, is regarded as among the drug choices for
methicillin-resistant Staphylococcus aureus (MRSA) infections. Few studies have evaluated …

Therapeutic drug concentrations of teicoplanin in clinical settings

SY Nah, JH Im, JY Yeo, JH Baek… - Infection & …, 2014 - synapse.koreamed.org
Background Teicoplanin is a glycopeptide antibiotic that is widely used in clinical practice for
the treatment of infections caused by drug-resistant Gram-positive bacteria. The aim of this …

Clinical efficacy and safety in patients treated with teicoplanin with a target trough concentration of 20 μg/mL using a regimen of 12 mg/kg for five doses within the …

T Ueda, Y Takesue, K Nakajima, K Ichiki… - BMC Pharmacology and …, 2020 - Springer
Background A trough concentration (C min)≥ 20 μg/mL of teicoplanin is recommended for
the treatment of serious methicillin-resistant Staphylococcus aureus (MRSA) infections …

Randomized comparison of serum teicoplanin concentrations following daily or alternate daily dosing in healthy adults

B Rouveix, F Jehl, H Drugeon, I Brumpt… - Antimicrobial agents …, 2004 - Am Soc Microbiol
Trough serum teicoplanin concentrations were compared in healthy adults following
intravenous administration of one of two regimens:(i) 12 mg/kg of body weight every 12 h for …

Clinical practice guidelines for therapeutic drug monitoring of teicoplanin: a consensus review by the Japanese Society of Chemotherapy and the Japanese Society of …

Y Hanai, Y Takahashi, T Niwa, T Mayumi… - Journal of …, 2022 - academic.oup.com
Background Owing to its low risk of adverse effects, teicoplanin has been extensively used
in patients with infections caused by MRSA. To promote the better management of patients …

Retrospective review of serum teicoplanin concentrations in clinical trials and their relationship to clinical outcome

A MacGowan, L White, D Reeves, I Harding - Journal of Infection and …, 1996 - Elsevier
Twenty-five published clinical studies were reviewed in which teicoplanin serum
concentrations were determined. A variety of assay methods were used, including bioassay …