Dysregulation of the immune system undoubtedly plays an important and, perhaps,
determining role in the COVID-19 pathogenesis. While the main treatment of the COVID-19 …

Abstract Coronavirus disease 2019 (COVID-19) infection which is caused by severe acute
respiratory syndrome coronavirus-2 (SARS-CoV-2) has led to a “public health emergency of …

One of the most serious viral outbreaks of the decade, infecting humans, originated from the
city of Wuhan, China, by the end of December 2019, has left the world shaken up. It is the …

AbsTRACT Novel coronavirus disease 2019 (COVID‑19) is a highly contagious, respiratory
disease caused by the newly emerged severe acute respiratory syndrome coronavirus 2 …

The pathogenesis of the SARS-CoV-2 virus is yet to be well understood. However, patients
with the virus show clinical manifestations which are very similar to those of SARS-CoV and …

Abstract The coronavirus disease-2019 (COVID-19) which caused by severe acute
respiratory syndrome-related coronavirus (SARS-CoV-2), is a pandemic threat to global …

To date, no vaccines or effective drugs have been approved to prevent or treat COVID-19
and the current standard care relies on supportive treatments. Therefore, based on the fast …

In the beginning of the third year of the fight against COVID-19, the virus remains at least still
one step ahead in the pandemic “war”. The key reasons are evolving lineages and …

SARS‐CoV‐2 causes multiorgan damage to vital organs and tissue that are known to be
due to a combination of tissue tropisms and cytokine‐mediated damage that it can incite in …

The effects of cytokine inhibition in the different phases of the severe coronavirus disease
2019 (COVID-19) are currently at the center of intense debate, and preliminary results from …