[HTML][HTML] Potential role of anti-interleukin (IL)-6 drugs in the treatment of COVID-19: rationale, clinical evidence and risks

S Crisafulli, V Isgrò, L La Corte, F Atzeni, G Trifiro - BioDrugs, 2020 - Springer
The epidemic due to severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)
infection has been spreading globally, raising increasing concerns. This public health …

Cytokine storm and COVID-19: a chronicle of pro-inflammatory cytokines

A Fara, Z Mitrev, RA Rosalia, BM Assas - Open biology, 2020 - royalsocietypublishing.org
Coronavirus disease 2019 (COVID-19) has swept the world, unlike any other pandemic in
the last 50 years. Our understanding of the disease has evolved rapidly since the outbreak; …

Coronavirus disease 2019 (COVID‐19): An overview of the immunopathology, serological diagnosis and management

AU Anka, MI Tahir, SD Abubakar… - Scandinavian …, 2021 - Wiley Online Library
SARS‐CoV‐2 is a novel human coronavirus responsible for the Coronavirus disease 2019
(COVID‐19) pandemic. Pneumonia and acute respiratory distress syndrome are the major …

[PDF][PDF] Discrimination of COVID‐19 from inflammation‐induced cytokine storm syndromes using disease‐related blood biomarkers

C Kessel, R Vollenberg… - Arthritis & …, 2021 - Wiley Online Library
Objective Infection with the novel coronavirus SARS–CoV‐2 triggers severe illness with high
mortality in a subgroup of patients. Such a critical course of COVID‐19 is thought to be …

Pathogenic T-cells and inflammatory monocytes incite inflammatory storms in severe COVID-19 patients

Y Zhou, B Fu, X Zheng, D Wang, C Zhao… - National Science …, 2020 - academic.oup.com
Pathogenic human coronavirus infections, such as severe acute respiratory syndrome CoV
(SARS-CoV) and Middle East respiratory syndrome CoV (MERS-CoV), cause high morbidity …

[HTML][HTML] Immunologic features in coronavirus disease 2019: functional exhaustion of T cells and cytokine storm

S Mahmoudi, M Rezaei, N Mansouri, M Marjani… - Journal of clinical …, 2020 - Springer
To the Editor: Since the emergence of Coronavirus Disease 2019 (COVID-19) caused by the
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in December 2019, the …

[HTML][HTML] Potential treatments for COVID-19 related cytokine storm-beyond corticosteroids

Y Miao, L Fan, JY Li - Frontiers in Immunology, 2020 - frontiersin.org
A novel virus, SARS-CoV-2, emerged in Wuhan in December 2019 and rapidly spread to
other cities in China and other countries. Several studies have summarized the clinical …

[HTML][HTML] Systemic and organ-specific immune-related manifestations of COVID-19

M Ramos-Casals, P Brito-Zerón… - Nature Reviews …, 2021 - nature.com
Immune-related manifestations are increasingly recognized conditions in patients with
COVID-19, with around 3,000 cases reported worldwide comprising more than 70 different …

The longitudinal immune response to coronavirus disease 2019: chasing the cytokine storm

AS Chau, AG Weber, NI Maria, S Narain… - Arthritis & …, 2021 - Wiley Online Library
The clinical progression of the severe acute respiratory syndrome coronavirus 2 infection,
coronavirus 2019 (COVID‐19), to critical illness is associated with an exaggerated immune …

[HTML][HTML] Role for anti-cytokine therapies in severe coronavirus disease 2019

LF Buckley, GF Wohlford, C Ting… - Critical care …, 2020 - journals.lww.com
Objectives: The causative agent for coronavirus disease 2019, severe acute respiratory
syndrome coronavirus 2, appears exceptional in its virulence and immunopathology. In …