G protein–coupled receptors (GPCRs) mediate responses to hormones and
neurotransmitters, as well as the senses of sight, smell, and taste. These remarkably …

Signal transduction is the means by which cells respond to variations in their environment. G-
protein-coupled receptors (GPCRs) are the largest family of cell-surface receptors …

The G protein coupled receptors (GPC-Rs) comprise a large superfamily of genes encoding
numerous receptors which all show common structural features, eg, seven putative …

G protein–coupled receptors (GPCRs) are versatile molecular machines that regulate the
majority of physiological responses to chemically diverse hormones and neurotransmitters …

G protein-coupled receptors (GPCRs) are critical regulators of human physiology and make
up the largest single class of therapeutic drug targets. Although GPCRs regulate highly …

During the past few years, crystallography of G protein–coupled receptors (GPCRs) has
experienced exponential growth, resulting in the determination of the structures of 16 distinct …

As one of the most successful therapeutic target families, G protein-coupled receptors
(GPCRs) have experienced a transformation from random ligand screening to knowledge …

G protein-coupled receptors (GPCRs), the largest family of human membrane proteins and
an important class of drug targets, play a role in maintaining numerous physiological …

The modulation of transmembrane signaling by G protein-coupled receptors (GPCRs)
constitutes the single most important therapeutic target in medicine. Drugs acting on GPCRs …

G-protein-coupled receptors (GPCRs) constitute the largest family of cell-surface molecules
involved in signal transmission. These receptors play key physiological roles and their …