[PDF][PDF] COVID-19: a new virus, but a familiar receptor and cytokine release syndrome
T Hirano, M Murakami - Immunity, 2020 - cell.com
Zhou et al.(Nature) and Hoffmann et al.(Cell) identify ACE2 as a SARS-CoV-2 receptor, and
the latter show its entry mechanism depends on cellular serine protease TMPRSS2. These …
the latter show its entry mechanism depends on cellular serine protease TMPRSS2. These …
Emerging roles of SARS-CoV-2 Spike-ACE2 in immune evasion and pathogenesis
The COVID-19 pandemic, caused by the SARS-CoV-2 virus, has caused an estimated 5
billion infections and 20 million deaths by respiratory failure. In addition to the respiratory …
billion infections and 20 million deaths by respiratory failure. In addition to the respiratory …
SARS-CoV-2 Entry Receptor ACE2 Is Expressed on Very Small CD45− Precursors of Hematopoietic and Endothelial Cells and in Response to Virus Spike Protein …
MZ Ratajczak, K Bujko, A Ciechanowicz… - Stem cell reviews and …, 2021 - Springer
Abstract Angiotensin-converting enzyme 2 (ACE2) plays an important role as a member of
the renin–angiotensin–aldosterone system (RAAS) in regulating the conversion of …
the renin–angiotensin–aldosterone system (RAAS) in regulating the conversion of …
[HTML][HTML] ACE2 in the era of SARS-CoV-2: controversies and novel perspectives
F Saponaro, G Rutigliano, S Sestito… - Frontiers in Molecular …, 2020 - frontiersin.org
Angiotensin-converting enzyme 2 (ACE2) is related to ACE but turned out to counteract
several pathophysiological actions of ACE. ACE2 exerts antihypertensive and …
several pathophysiological actions of ACE. ACE2 exerts antihypertensive and …
SARS-CoV-2 cellular entry is independent of the ACE2 cytoplasmic domain signaling
T Karthika, J Joseph, VRA Das, N Nair, P Charulekha… - Cells, 2021 - mdpi.com
Recently emerged severe acute respiratory syndrome coronavirus (SARS-CoV)-1 and-2
initiate virus infection by binding of their spike glycoprotein with the cell-surface receptor …
initiate virus infection by binding of their spike glycoprotein with the cell-surface receptor …
[HTML][HTML] SARS-CoV-2 pandemic and research gaps: Understanding SARS-CoV-2 interaction with the ACE2 receptor and implications for therapy
The COVID-19 pandemic is an emerging threat to global public health. While our current
understanding of COVID-19 pathogenesis is limited, a better understanding will help us …
understanding of COVID-19 pathogenesis is limited, a better understanding will help us …
ACE2: the major cell entry receptor for SARS-CoV-2
Despite the unprecedented effort of the scientific community, the novel SARS-CoV-2 virus
has infected more than 46 million people worldwide, killing over one million two hundred …
has infected more than 46 million people worldwide, killing over one million two hundred …
The SARS-CoV-2 exerts a distinctive strategy for interacting with the ACE2 human receptor
The COVID-19 disease has plagued over 200 countries with over three million cases and
has resulted in over 200,000 deaths within 3 months. To gain insight into the high infection …
has resulted in over 200,000 deaths within 3 months. To gain insight into the high infection …
SARS-CoV-2 down-regulates ACE2 through lysosomal degradation
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) utilizes its Spike (S)
glycoprotein to bind to the angiotensin-converting enzyme 2 (ACE2) receptor for cellular …
glycoprotein to bind to the angiotensin-converting enzyme 2 (ACE2) receptor for cellular …
Increasing host cellular receptor—angiotensin‐converting enzyme 2 expression by coronavirus may facilitate 2019‐nCoV (or SARS‐CoV‐2) infection
MW Zhuang, Y Cheng, J Zhang… - Journal of medical …, 2020 - Wiley Online Library
The ongoing outbreak of a new coronavirus (2019‐nCoV, or severe acute respiratory
syndrome coronavirus 2 [SARS‐CoV‐2]) has caused an epidemic of the acute respiratory …
syndrome coronavirus 2 [SARS‐CoV‐2]) has caused an epidemic of the acute respiratory …