[HTML][HTML] SARS-CoV-2 Omicron spike mediated immune escape and tropism shift

R Gupta - Research square, 2022 - ncbi.nlm.nih.gov
Abstract The SARS-CoV-2 Omicron BA. 1 variant emerged in late 2021 and is characterised
by multiple spike mutations across all spike domains. Here we show that Omicron BA. 1 has …

[HTML][HTML] Neutralization and stability of SARS-CoV-2 Omicron variant

C Zeng, JP Evans, P Qu, J Faraone, YM Zheng… - biorxiv, 2021 - ncbi.nlm.nih.gov
Abstract The SARS-CoV-2 B. 1.1. 529/Omicron variant was first characterized in South Africa
and was swiftly designated a variant of concern 1. Of great concern is its high number of …

Mucosal boosting enhances vaccine protection against SARS-CoV-2 in macaques

K McMahan, F Wegmann, M Aid, M Sciacca, J Liu… - Nature, 2024 - nature.com
A limitation of current SARS-CoV-2 vaccines is that they provide minimal protection against
infection with current Omicron subvariants,, although they still provide protection against …

Omicron variant (B. 1.1. 529) of SARS-CoV-2: Threat for the elderly?

VP Chavda, V Apostolopoulos - Maturitas, 2022 - maturitas.org
The evolvement of coronavirus variants is socially unacceptable but understandable in a
world that has grown tired of playing defence against “severe acute respiratory syndrome …

Increased immune escape of the new SARS-CoV-2 variant of concern Omicron

J Hu, P Peng, X Cao, K Wu, J Chen, K Wang… - Cellular & Molecular …, 2022 - nature.com
On 24 November, a new detected variant B. 1.1. 529 of SARS-CoV-2 by South Africa was
reported to WHO. After only 2 days, this variant was designated as “variant of concern”(VOC) …

COVID‐19: Omicron–the latest, the least virulent, but probably not the last variant of concern of SARS‐CoV‐2

H Brüssow - Microbial Biotechnology, 2022 - Wiley Online Library
The Omicron variant rapidly became the dominant SARS‐CoV‐2 strain in South Africa and
elsewhere. This review explores whether this rise was due to an increased transmission of …

SARS-CoV-2 spike T cell responses induced upon vaccination or infection remain robust against Omicron

R Keeton, MB Tincho, A Ngomti, R Baguma, N Benede… - MedRxiv, 2021 - medrxiv.org
Summary The SARS-CoV-2 Omicron variant has multiple Spike (S) protein mutations that
contribute to escape from the neutralizing antibody responses, and reducing vaccine …

Omicron sub-lineages BA. 4/BA. 5 escape BA. 1 infection elicited neutralizing immunity

K Khan, F Karim, Y Ganga, M Bernstein, Z Jule… - MedRxiv, 2022 - medrxiv.org
The SARS-CoV-2 Omicron (B. 1.1. 529) variant first emerged as the BA. 1 sub-lineage, with
extensive escape from neutralizing immunity elicited by previous infection with other …

[PDF][PDF] Omicron strain spreads with the doubling time of 3.2—3.6 days in South Africa province of Gauteng that achieved herd immunity to Delta variant

F Grabowski, M Kochańczyk, T Lipniacki - MedRxiv, 2021 - academia.edu
Omicron, the novel, highly mutated SARS‐CoV‐2 Variant of Concern (belonging to the
Pango lineage B. 1.1. 529), was first collected on November 8, 2021, in Gauteng province of …

Vaccine protection against the SARS-CoV-2 Omicron variant in macaques

A Chandrashekar, J Yu, K McMahan, C Jacob-Dolan… - Cell, 2022 - cell.com
The rapid spread of the SARS-CoV-2 Omicron (B. 1.1. 529) variant, including in highly
vaccinated populations, has raised important questions about the efficacy of current …