Oral nirmatrelvir/ritonavir is approved as treatment for acute COVID‐19, but the effect of treatment during acute infection on risk of Long COVID is unknown. We hypothesized that …
S Congdon, Z Narrowe, N Yone, J Gunn, Y Deng… - Scientific reports, 2023 - nature.com
We conducted a retrospective cohort study to assess whether treatment with nirmatrelvir/ritonavir was associated with a reduced risk of long COVID. We enrolled 500 …
Background Our objective was to evaluate the real world effectiveness of nirmatrelvir/ritonavir to prevent severe COVID-19 while Omicron and its subvariants …
Background: In the EPIC-HR trial, nirmatrelvir plus ritonavir led to an 88% reduction in hospitalization or death among unvaccinated outpatients with early COVID-19. Clinical …
J Hammond, RJ Fountaine, C Yunis… - … England Journal of …, 2024 - Mass Medical Soc
Background Nirmatrelvir in combination with ritonavir is an antiviral treatment for mild-to- moderate coronavirus disease 2019 (Covid-19). The efficacy of this treatment in patients …
SE Smith-Jeffcoat, JE Biddle, HK Talbot… - Clinical Infectious …, 2024 - academic.oup.com
Abstract Background Nirmatrelvir/ritonavir (N/R) reduces severe outcomes from coronavirus disease 2019 (COVID-19); however, rebound after treatment has been reported. We …
Long Covid–the disease encompassing the post-acute sequelae of SARS-CoV-2 (PASC)— affects millions of people around the world. Prevention of PASC is an urgent public health …
Background: Efforts to understand the impact of SARS-CoV-2 variants, vaccine status, and treatment on the development and persistence of Long COVID have intensified. Methods …
H Zhang, X Tan, Z Zhang, C Wang, H Shi, Y Li… - BMC Infectious …, 2024 - Springer
Background There is an urgent need for therapeutic strategies for inpatients with severe or critical COVID-19. The evaluation of the clinical benefits of nirmatrelvir and ritonavir (Nmr/r) …