Doherty JL, O'Donovan MC, Owen MJ. Recent genomic advances in schizoprenia. Recent
studies have supported the hypothesis based upon expectations from population genetics …

Objectives: Schizophrenia is a severe psychiatric disease affecting about 1% of the general
population. The relative contribution of genetic factors has been estimated to be up to 80 …

Schizophrenia is widely held to stem from the combined effects of multiple common
polymorphisms, each with a small impact on disease risk. We suggest an alternative view …

Understanding the genetic basis of schizophrenia continues to be major challenge. The
research done during the last two decades has provided several candidate genes which …

Growing genetic evidence is converging in favor of common pathogenic mechanisms for
autism spectrum disorders (ASD), intellectual disability (ID or mental retardation) and …

The heritability of schizophrenia is well established, and has motivated the search for
genetic variation that contributes to susceptibility. Recent progress from both genome-wide …

The work conducted using genome-wide approaches during the past several years has
invigorated the field, and represents the dawn of molecular genetics of schizophrenia. The …

Schizophrenia and bipolar disorder have a largely unknown pathophysiology and etiology,
but they are highly heritable. Although linkage and association studies have identified a …

There has been substantial progress in understanding the genetics of schizophrenia over
the past 15 years. This has revealed a highly polygenic condition with the majority of the …

After two decades of frustration, genetic studies of schizophrenia have entered an era of
spectacular success. Advances in genotyping technologies and high throughput …