Injectable block copolymer hydrogels: achievements and future challenges for biomedical applications

CT Huynh, MK Nguyen, DS Lee - Macromolecules, 2011 - ACS Publications
In the past two decades, physical polymeric hydrogels have been extensively explored for
biomedical applications, such as drug delivery and tissue engineering. These hydrogels …

In situ gelling pH-and temperature-sensitive biodegradable block copolymer hydrogels for drug delivery

NK Singh, DS Lee - Journal of Controlled Release, 2014 - Elsevier
Stimuli-sensitive injectable polymeric hydrogels have been extensively investigated during
the past decade as bioactive agent delivery vehicles and for tissue engineering applications …

In situ gelling stimuli-sensitive block copolymer hydrogels for drug delivery

C He, SW Kim, DS Lee - Journal of controlled release, 2008 - Elsevier
Stimuli-sensitive block copolymer hydrogels, which are reversible polymer networks formed
by physical interactions and exhibit a sol–gel phase-transition in response to external …

Injectable hydrogels as unique biomedical materials

L Yu, J Ding - Chemical Society Reviews, 2008 - pubs.rsc.org
A concentrated fish soup could be gelled in the winter and re-solled upon heating. In
contrast, some synthetic copolymers exhibit an inverse sol–gel transition with spontaneous …

Hydrogels in a historical perspective: From simple networks to smart materials

SJ Buwalda, KWM Boere, PJ Dijkstra, J Feijen… - Journal of controlled …, 2014 - Elsevier
Over the past decades, significant progress has been made in the field of hydrogels as
functional biomaterials. Biomedical application of hydrogels was initially hindered by the …

Designing injectable, covalently cross‐linked hydrogels for biomedical applications

M Patenaude, NMB Smeets… - Macromolecular rapid …, 2014 - Wiley Online Library
Hydrogels that can form spontaneously via covalent bond formation upon injection in vivo
have recently attracted significant attention for their potential to address a variety of …

Hydrogels for therapeutic delivery: current developments and future directions

SJ Buwalda, T Vermonden, WE Hennink - Biomacromolecules, 2017 - ACS Publications
Hydrogels are attractive materials for the controlled release of therapeutics because of their
capacity to embed biologically active agents in their water-swollen network. Recent …

Injectable hydrogels

DJ Overstreet, D Dutta, SE Stabenfeldt… - Journal of Polymer …, 2012 - Wiley Online Library
Hydrogels are promising for a variety of medical applications due to their high water content
and mechanical similarity to natural tissues. When made injectable, hydrogels can reduce …

Hybrid hydrogels for biomedical applications

LL Palmese, RK Thapa, MO Sullivan… - Current opinion in chemical …, 2019 - Elsevier
Highlights•Nano/microstructures can be incorporated into the hydrogels by various physical
or chemical cross-linking methods.•Nano/microstructures can enhance the mechanical …

Recent progress in biopolymer-based hydrogel materials for biomedical applications

A Mahmood, D Patel, B Hickson… - International Journal of …, 2022 - mdpi.com
Hydrogels from biopolymers are readily synthesized, can possess various characteristics for
different applications, and have been widely used in biomedicine to help with patient …