[PDF][PDF] Glycomic approaches toward drug development: therapeutically exploring the glycosaminoglycanome

B Gesslbauer, AJ Kungl - Current opinion in molecular …, 2006 - researchgate.net
The science of decoding the information contained within complex glycan structures is
commonly referred to as' glycomics'. Information flow is usually governed by the binding of …

Mouse and human glycomes

SJ North, S Chalabi, M Sutton-Smith, A Dell… - Handbook of …, 2010 - Elsevier
Publisher Summary Glycomics is the scientific effort to explore, characterize, and study all of
the carbohydrate structures produced by a defined system. This can be performed at the …

[HTML][HTML] Glycans in biotechnology and the pharmaceutical industry

CR Bertozzi, HH Freeze, A Varki… - Essentials of Glycobiology …, 2009 - ncbi.nlm.nih.gov
Glycans are components of many biotherapeutic agents, ranging from natural products to
molecules based on rational design to recombinant glycoproteins. The glycan components …

Structural glycobiology in medicine: Carbohydrates and glycoconjugates

PM Rudd, RA Dwek - Current Opinion in Structural Biology, 2006 - academia.edu
This issue of Current Opinion in Structural Biology is timely, as glycobiology has now finally
taken its place as an integral part of biochemistry and biology. At the present time, many new …

A guide into glycosciences: how chemistry, biochemistry and biology cooperate to crack the sugar code

D Solis, NV Bovin, AP Davis, J Jiménez-Barbero… - … et Biophysica Acta (BBA …, 2015 - Elsevier
Background The most demanding challenge in research on molecular aspects within the
flow of biological information is posed by the complex carbohydrates (glycan part of cellular …

[图书][B] Glycosylation

S Petrescu - 2012 - books.google.com
This book, outlining the concepts of glycobiology, is a suite of reviews and articles written by
a team of acknowledged researchers and covers some of the key topics in the field …

[图书][B] Synthesis and biological applications of glycoconjugates

O Renaudet, N Spinelli - 2011 - books.google.com
The interactions between carbohydrates and proteins have been extensively explored in a
wide range of physiological and pathological processes over several decades. The recent …

Breakthrough of glycobiology in the 21st century

G Mahara, C Tian, X Xu, J Zhu - Frontiers in Immunology, 2023 - frontiersin.org
As modern medicine began to emerge at the turn of the 20th century, glycan-based
therapies advanced. DNA-and protein-centered therapies became widely available. The …

Towards defining the role of glycans as hardware in information storage and transfer: basic principles, experimental approaches and recent progress

D Solís, J Jiménez-Barbero, H Kaltner, A Romero… - Cells Tissues …, 2001 - karger.com
The term 'code'in biological information transfer appears to be tightly and hitherto exclusively
connected with the genetic code based on nucleotides and translated into functional …

Glycosaminoglycans and glycomimetics in the central nervous system

D Rowlands, K Sugahara, JCF Kwok - Molecules, 2015 - mdpi.com
With recent advances in the construction of synthetic glycans, selective targeting of the
extracellular matrix (ECM) as a potential treatment for a wide range of diseases has become …