Aging is an inevitable outcome of life, characterized by a progressive decline in tissue and
organ function. At a molecular level, it is marked by the gradual alterations of biomolecules …

Biological aging is characterized by irreversible cell cycle blockade, a decreased capacity
for tissue regeneration, and an increased risk of age-related diseases and mortality. A …

Aging is a complex process that results in compromised biological functions of the organism
and increased susceptibility to disease and death. Although the molecular basis of aging is …

Aging is associated with a wide range of human disorders, including cancer, diabetes,
cardiovascular, and neurodegenerative diseases. Long thought to be an inexorable road …

Recent statistics indicate that the human population is ageing rapidly. Healthy, but also
diseased, elderly people are increasing. This trend is particularly evident in Western …

Aging represents the multifactorial decline in physiological function of every living organism.
Over the past decades, several hallmarks of aging have been defined, including epigenetic …

Ageing is the most complex phenotype currently known, since it becomes manifest in all
organs and tissues, affects an organism's entire physiology, impacts function at all levels …

The role of epigenetics in aging and age-related diseases is a key issue in molecular
physiology and medicine because certain epigenetic factors are thought to mediate, at least …

Cell senescence, which is an irreversible state of cell proliferative arrest, has emerged as a
potentially important contributor to tissue dysfunction and organismal ageing. Cell …

Aging is an important risk factor for several human diseases such as cancer, cardiovascular
disease and neurodegenerative disorders, resulting from a combination of genetic and …