Aging is an inevitable outcome of life, characterized by progressive decline in tissue and organ function and increased risk of mortality. Accumulating evidence links aging to genetic …
R Stegeman, VM Weake - Journal of molecular biology, 2017 - Elsevier
Genome-wide studies of aging have identified subsets of genes that show age-related changes in expression. Although the types of genes that are age regulated vary among …
Aging is one of the most important biological processes and is a known risk factor for many age-related diseases in human. Studying age-related transcriptomic changes in tissues …
A Guillaumet-Adkins, Y Yañez… - Oxidative medicine …, 2017 - Wiley Online Library
Aging is a multifactorial process characterized by the progressive loss of physiological functions, leading to an increased vulnerability to age‐associated diseases and finally to …
M Yu, H Zhang, B Wang, Y Zhang, X Zheng, B Shao… - Cells, 2021 - mdpi.com
Aging is a fundamental biological process accompanied by a general decline in tissue function. Indeed, as the lifespan increases, age-related dysfunction, such as cognitive …
Aging, as a complex process involving multiple cellular and molecular pathways, is known to be exacerbated by various stresses. Because responses to these stresses, such as oxidative …
Aging is characterized by a progressive loss of physiological integrity, leading to impaired function and increased vulnerability to death. This deterioration is the primary risk factor for …
RA Veitia, DR Govindaraju, S Bottani, JA Birchler - Trends in Cell Biology, 2017 - cell.com
Aging involves a progressive decline of metabolic function and an increased incidence of late-onset degenerative disorders and cancer. To a large extent, these processes are …
C Huidobro, AF Fernandez, MF Fraga - Molecular Aspects of Medicine, 2013 - Elsevier
Growth and development of higher organisms are regulated by the orchestrated change of epigenetic marks over time. In addition, there is also an epigenetic variation without any …