GABAA Modulation of S100B Secretion in Acute Hippocampal Slices and Astrocyte Cultures

AFK Vizuete, F Hansen, C Da Ré, MB Leal… - Neurochemical …, 2019 - Springer
Astrocytes are the major glial cells in brain tissue and are involved, among many functions,
ionic and metabolic homeostasis maintenance of synapses. These cells express receptors …

S100B Secretion in Acute Brain Slices: Modulation by Extracellular Levels of Ca2+ and K+

P Nardin, L Tortorelli, A Quincozes-Santos… - Neurochemical …, 2009 - Springer
Hippocampal slices have been widely used to investigate electrophysiological and
metabolic neuronal parameters, as well as parameters of astroglial activity including protein …

Relevance of astrocytic activation to reductions of astrocytic GABAA receptors

N Tateishi, T Shimoda, J Manako, S Katsumata… - Brain research, 2006 - Elsevier
Although astrocytes express γ-aminobutyric acid subtype-A (GABAA) receptors in the mature
brain, GABAA receptor expression in a cultivation state remains controversial. In this study …

Arundic acid (ONO-2526) inhibits stimulated-S100B secretion in inflammatory conditions

AFK Vizuete, J de Lima Cordeiro, JD Neves… - Neuroscience …, 2021 - Elsevier
Astrocytes respond to injury by modifying the expression profile of several proteins,
including the S100 calcium-binding protein B (S100B), assumed to be a marker as well as a …

β-Hydroxy-butyrate alters the extracellular content of S100B in astrocyte cultures

M Leite, JK Frizzo, P Nardin, LMV De Almeida… - Brain research …, 2004 - Elsevier
Astrocytes have a variety of roles in maintaining neural tissue physiology, including
energetic support, uptake and metabolism of glutamate and secretion of neurotrophic …

High glutamate decreases S100B secretion by a mechanism dependent on the glutamate transporter

F Tramontina, MC Leite, D Gonçalves… - Neurochemical …, 2006 - Springer
Several molecules have been shown to be involved in glial-neuronal communication,
including S100B, an astrocyte-derived neurotrophic cytokine. Extracellular S100B protects …

Glutamate uptake is stimulated by extracellular S100B in hippocampal astrocytes.

F Tramontina, AC Tramontina, DF Souza… - Cellular and …, 2006 - europepmc.org
1. S100B is a calcium-binding protein expressed and secreted by astrocytes, which has
been implicated in glial-neuronal communication. Extracellular S100B appears to protect …

Gap junction inhibitors modulate S100B secretion in astrocyte cultures and acute hippocampal slices

MC Leite, F Galland, DF de Souza… - Journal of …, 2009 - Wiley Online Library
Astrocytes sense, integrate, and respond to stimuli generated by neurons or neural injury;
this response involves gap junction (GJ) communication. Neuronal vulnerability to injury …

High glutamate decreases S100B secretion stimulated by serum deprivation in astrocytes

D Gonçalves, J Karl, M Leite, L Rotta, C Salbego… - …, 2002 - journals.lww.com
S100B is a calcium-binding protein expressed and secreted by astrocytes, playing a
neurotrophic role in neighboring cells. A protective role of the S100B against glutamate …

S100B Secretion in Astrocytes, Unlike C6 Glioma Cells, Is Downregulated by Lactate

NG Selistre, L Rodrigues, BC Federhen, V Gayger-Dias… - Metabolites, 2023 - mdpi.com
S100B is a calcium-binding protein produced and secreted by astrocytes in response to
various extracellular stimuli. C6 glioma cells are a lineage commonly employed for astroglial …