Osteopetrosis is a rare skeletal condition characterized by skeletal sclerosis caused by
aberrant osteoclast-mediated bone resorption. Three clinically distinct forms of osteopetrosis …

Medical treatments of osteopetrosis have attempted to improve hematologic function, reduce
the osteosclerotic condition, and/or improve immune function. Prednisone therapy has …

Osteopetrosis is an inherited skeletal condition characterized by increased bone
radiodensity. There are three clinical groups: infantile-malignant autosomal recessive, fatal …

Osteopetroses are rare human genetic disorders due to markedly decreased bone
resorption. To date, the only gene whose inactivation was known to be responsible for …

Osteopetrosis is a sclerosing bone dysplasia characterized by hard, brittle bone secondary
to dysfunctional osteoclast resorption. The three main forms are malignant autosomal …

Osteopetrosis (OPT) is a life-threatening disease characterized by increased bone mass
caused by diminished osteoclast function/differentiation. The autosomal recessive forms …

Osteopetrosis is a metabolic bone disease characterized by a systemic increase in skeletal
mass. It results from a defect in the production or function of osteoclasts and is inherited in …

Osteopetrosis is a metabolic bone disease inherited in a number of species including
human beings and characterized by a generalized increase in skeletal density detected …

Two principal types of osteopetrosis have been distinguished. One is the dominantly
inherited, relatively benign condition which is often detected radiologically in asymptomatic …

Osteopetrosis is a heterogeneous family of rare human genetic disorders due to markedly
decreased bone resorption. It is one among disorders causing osteosclerosis of the …