N Vaninov - Nature Reviews Immunology, 2020 - nature.com
Acute respiratory distress syndrome (ARDS) and robust cytokine storm are the hallmark of severe COVID-19 cases. Using single-cell RNA sequencing of bronchoalveolar lavage fluid …
C Yao, SA Bora, T Parimon, T Zaman, OA Friedman… - Cell reports, 2021 - cell.com
Recent studies have demonstrated immunologic dysfunction in severely ill coronavirus disease 2019 (COVID-19) patients. We use single-cell RNA sequencing (scRNA-seq) to …
M Anft, K Paniskaki, A Blazquez-Navarro, A Doevelaar… - Molecular Therapy, 2020 - cell.com
Preventing the progression to acute respiratory distress syndrome (ARDS) in COVID-19 is an unsolved challenge. The involvement of T cell immunity in this exacerbation remains …
Y Zhou, B Fu, X Zheng, D Wang, C Zhao… - National Science …, 2020 - academic.oup.com
Pathogenic human coronavirus infections, such as severe acute respiratory syndrome CoV (SARS-CoV) and Middle East respiratory syndrome CoV (MERS-CoV), cause high morbidity …
G Xu, F Qi, H Li, Q Yang, H Wang, X Wang, X Liu… - Cell discovery, 2020 - nature.com
Understanding the mechanism that leads to immune dysfunction in severe coronavirus disease 2019 (COVID-19) is crucial for the development of effective treatment. Here, using …
PA Szabo, P Dogra, JI Gray, SB Wells, TJ Connors… - Immunity, 2021 - cell.com
Immune response dynamics in coronavirus disease 2019 (COVID-19) and their severe manifestations have largely been studied in circulation. Here, we examined the relationship …
The pathogenesis of pandemic coronavirus disease-2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) likely depends heavily on …
R Jeannet, T Daix, R Formento, J Feuillard… - Intensive care …, 2020 - Springer
Dear Editor, SARS-CoV-2 infection is associated with marked lymphopenia that correlates with morbidity and mortality [1, 2]. Here, we present the first report on serial …
Abstract Analysis of human blood immune cells provides insights into the coordinated response to viral infections such as severe acute respiratory syndrome coronavirus 2, which …