[HTML][HTML] Recent insight into SARS-CoV2 immunopathology and rationale for potential treatment and preventive strategies in COVID-19

S Lega, S Naviglio, S Volpi, A Tommasini - Vaccines, 2020 - mdpi.com
As the outbreak of the new coronavirus (SARS-CoV-2) infection is spreading globally, great
effort is being made to understand the disease pathogenesis and host factors that …

Downregulated gene expression spectrum and immune responses changed during the disease progression in patients with COVID-19

Y Ouyang, J Yin, W Wang, H Shi, Y Shi… - Clinical infectious …, 2020 - academic.oup.com
Abstract Background The World Health Organization characterizes novel coronavirus
disease 2019 (COVID-19), which is caused by severe acute respiratory syndrome …

[HTML][HTML] Interleukin-6 is a biomarker for the development of fatal severe acute respiratory syndrome coronavirus 2 pneumonia

A Santa Cruz, A Mendes-Frias, AI Oliveira… - Frontiers in …, 2021 - frontiersin.org
Hyper-inflammatory responses induced by severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) are a major cause of disease severity and death. Predictive prognosis …

Characteristics of inflammatory factors and lymphocyte subsets in patients with severe COVID‐19

M Ni, FB Tian, DD Xiang, B Yu - Journal of medical virology, 2020 - Wiley Online Library
To investigate the inflammatory factors and lymphocyte subsets which play an important role
in the course of severe coronavirus disease 2019 (COVID‐19). A total of 27 patients with …

[HTML][HTML] Pro-and anti-inflammatory responses in severe COVID-19-induced acute respiratory distress syndrome—an observational pilot study

Q Notz, M Schmalzing, F Wedekink… - Frontiers in …, 2020 - frontiersin.org
Objectives The severity of Coronavirus Disease 2019 (COVID-19) is largely determined by
the immune response. First studies indicate altered lymphocyte counts and function …