An interferon‐γ‐related cytokine storm in SARS patients

KJ Huang, IJ Su, M Theron, YC Wu… - Journal of medical …, 2005 - Wiley Online Library
Fourteen cytokines or chemokines were analyzed on 88 RT‐PCR‐confirmed severe acute
respiratory syndrome (SARS) patients. IFN‐γ, IL‐18, TGF‐β, IL‐6, IP‐10, MCP‐1, MIG, and IL …

Analysis of serum cytokines in patients with severe acute respiratory syndrome

Y Zhang, J Li, Y Zhan, L Wu, X Yu, W Zhang… - Infection and …, 2004 - Am Soc Microbiol
Severe acute respiratory syndrome (SARS) is an acute infectious disease of the respiratory
system. Although a novel coronavirus has been identified as the causative agent of SARS …

Cytokine regulation in SARS coronavirus infection compared to other respiratory virus infections

T Okabayashi, H Kariwa, S Yokota, S Iki… - Journal of medical …, 2006 - Wiley Online Library
The pathogenesis of severe acute respiratory syndrome (SARS) is poorly understood and
cytokine dysregulation has been suggested as one relevant mechanism to be explored. We …

Clinical manifestations and inflammatory cytokine responses in patients with severe acute respiratory syndrome.

WH Sheng, BL Chiang, SC Chang, HN Ho… - Journal of the …, 2005 - europepmc.org
Background and purpose Severe acute respiratory syndrome (SARS) is a highly
transmissible disease with significant morbidity and mortality. Death from SARS is most often …

Plasma inflammatory cytokines and chemokines in severe acute respiratory syndrome

CK Wong, CWK Lam, AKL Wu, WK Ip… - Clinical & …, 2004 - academic.oup.com
Severe acute respiratory syndrome (SARS) is a recently emerged infectious disease caused
by a novel coronavirus, but its immunopathological mechanisms have not yet been fully …

Temporal changes in cytokine/chemokine profiles and pulmonary involvement in severe acute respiratory syndrome

JY CHIEN, PR HSUEH, WC CHENG, CJ YU… - …, 2006 - Wiley Online Library
Objective and background: Pathological changes in severe acute respiratory syndrome
(SARS) suggest that SARS sequelae are associated with dysregulation of cytokine and …

A probable role for IFN-γ in the development of a lung immunopathology in SARS

M Theron, KJ Huang, YW Chen, CC Liu, HY Lei - Cytokine, 2005 - Elsevier
Recent work carried out in our laboratory showed the existence of a cytokine storm in SARS
patients, dominated by Th1-type mediators. We thus hypothesized that IFN-γ may play a …

[HTML][HTML] Clinical manifestations, laboratory findings, and treatment outcomes of SARS patients

JT Wang, WH Sheng, CT Fang, YC Chen… - Emerging infectious …, 2004 - ncbi.nlm.nih.gov
Clinical and laboratory data on severe acute respiratory syndrome (SARS), particularly on
the temporal progression of abnormal laboratory findings, are limited. We conducted a …

Characterization of cytokine/chemokine profiles of severe acute respiratory syndrome

Y Jiang, J Xu, C Zhou, Z Wu, S Zhong, J Liu… - American journal of …, 2005 - atsjournals.org
Rationale: There is currently no optimal treatment or effective drug for severe acute
respiratory syndrome (SARS), because the immunopathologic mechanism is poorly …

Autoantibodies against human epithelial cells and endothelial cells after severe acute respiratory syndrome (SARS)‐associated coronavirus infection

YH Yang, YH Huang, YH Chuang… - Journal of medical …, 2005 - Wiley Online Library
The severe acute respiratory syndrome (SARS) is caused by infection with the SARS‐
associated coronavirus (SARS‐CoV) and characterized by severe pulmonary inflammation …