COVID-19 displays diverse disease severities and symptoms including acute systemic
inflammation and hypercytokinemia, with subsequent dysregulation of immune cells …

Objectives Emerging evidence of dysregulation of the myeloid cell compartment urges
investigations on neutrophil characteristics in coronavirus disease 2019 (COVID‐19). We …

The Coronavirus Disease 2019 (COVID-19) is caused by the betacoronavirus Severe Acute
Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) virus that can mediate asymptomatic or …

Most patients with coronavirus disease 2019 (COVID-19) experience asymptomatic disease
or mild symptoms, but some have critical symptoms requiring intensive care. It is important to …

Abstract Corona virus disease 2019 (COVID-19) patients with severe immune abnormalities
are at risk of cytokine release syndrome (CRS). The definition, prevention, and treatment of …

Background Increased inflammation is a hallmark of COVID-19, with pulmonary and
systemic inflammation identified in multiple cohorts of patients. Definitive cellular and …

The pathogenesis of coronavirus disease 2019 (COVID-19), caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), is still not fully unraveled. Though …

Infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the cause of
coronavirus disease 2019 (COVID-19), has resulted in a pandemic that has had widespread …

Unusually for a viral infection, the immunological phenotype of severe COVID-19 is
characterised by a depleted lymphocyte and elevated neutrophil count, with the neutrophil …

Proper management of COVID-19 mandates better understanding of disease pathogenesis.
The sudden clinical deterioration 7–8 days after initial symptom onset suggests that severe …