[HTML][HTML] Role of inflammatory cytokines in COVID-19 patients: A review on molecular mechanisms, immune functions, immunopathology and immunomodulatory drugs …

AA Rabaan, SH Al-Ahmed, J Muhammad, A Khan… - Vaccines, 2021 - mdpi.com
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), is a severe pandemic of the current century. The vicious …

[HTML][HTML] Monocyte activation in systemic Covid-19 infection: Assay and rationale

FO Martinez, TW Combes, F Orsenigo, S Gordon - EBioMedicine, 2020 - thelancet.com
Mononuclear phagocytes are a widely distributed family of cells contributing to innate and
adaptive immunity. Circulating monocytes and tissue macrophages participate in all stages …

A neutrophil activation signature predicts critical illness and mortality in COVID-19

ML Meizlish, AB Pine, JD Bishai, G Goshua… - Blood …, 2021 - ashpublications.org
Pathologic immune hyperactivation is emerging as a key feature of critical illness in COVID-
19, but the mechanisms involved remain poorly understood. We carried out proteomic …

[HTML][HTML] Neutrophils and neutrophil extracellular traps drive necroinflammation in COVID-19

B Tomar, HJ Anders, J Desai, SR Mulay - Cells, 2020 - mdpi.com
The COVID-19 pandemic is progressing worldwide with an alarming death toll. There is an
urgent need for novel therapeutic strategies to combat potentially fatal complications …

Can we use interleukin-6 (IL-6) blockade for coronavirus disease 2019 (COVID-19)-induced cytokine release syndrome (CRS)?

B Liu, M Li, Z Zhou, X Guan, Y Xiang - Journal of autoimmunity, 2020 - Elsevier
The emergent outbreak of coronavirus disease 2019 (COVID-19) has caused a global
pandemic. Acute respiratory distress syndrome (ARDS) and multiorgan dysfunction are …

[HTML][HTML] Cell death in coronavirus infections: Uncovering its role during COVID-19

A Paolini, R Borella, S De Biasi, A Neroni, M Mattioli… - Cells, 2021 - mdpi.com
Cell death mechanisms are crucial to maintain an appropriate environment for the
functionality of healthy cells. However, during viral infections, dysregulation of these …

[HTML][HTML] COVID-19: towards understanding of pathogenesis

W Cao, T Li - Cell research, 2020 - nature.com
The pandemic of coronavirus disease 2019 (COVID-19) is spreading rapidly. Although the
cause was quickly identified as a new coronavirus named SARS-CoV-2, our knowledge of …

Immunopathology and immunotherapeutic strategies in severe acute respiratory syndrome coronavirus 2 infection

S Keam, D Megawati, SK Patel, R Tiwari… - Reviews in Medical …, 2020 - Wiley Online Library
The outbreak of coronavirus disease 2019 (COVID‐19) and pandemic, caused by severe
acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), has become a major concern …

[HTML][HTML] A longitudinal study of immune cells in severe COVID-19 patients

D Payen, M Cravat, H Maadadi, C Didelot… - Frontiers in …, 2020 - frontiersin.org
Little is known about the time-dependent immune responses in severe COVID-19. Data of
15 consecutive patients were sequentially recorded from intensive care unit admission …

Role of monocytes/macrophages in Covid-19 pathogenesis: implications for therapy

J Gómez-Rial, I Rivero-Calle, A Salas… - Infection and Drug …, 2020 - Taylor & Francis
cov-Abstract Emerging studies from SARS-CoV-2-infected patients indicate a preponderant
role of monocytes/macrophages in the pathogenesis of this viral infection, in a similar way to …