Neutralization of Omicron BA. 1, BA. 2, and BA. 3 SARS-CoV-2 by 3 doses of BNT162b2 vaccine

C Kurhade, J Zou, H Xia, H Cai, Q Yang… - Nature …, 2022 - nature.com
The newly emerged Omicron SARS-CoV-2 has several distinct sublineages including BA. 1,
BA. 2, and BA. 3. BA. 1 accounts for the initial surge and is being replaced by BA. 2, whereas …

[HTML][HTML] Longitudinal analysis of serum neutralization of SARS-CoV-2 Omicron BA. 2, BA. 4, and BA. 5 in patients receiving monoclonal antibodies

T Bruel, K Stéfic, Y Nguyen, D Toniutti, I Staropoli… - Cell Reports …, 2022 - cell.com
The emergence of Omicron sublineages impacts the therapeutic efficacy of anti-severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) monoclonal antibodies (mAbs) …

[HTML][HTML] Duration of BA. 5 neutralization in sera and nasal swabs from SARS-CoV-2 vaccinated individuals, with or without omicron breakthrough infection

D Planas, I Staropoli, F Porot, F Guivel-Benhassine… - Med, 2022 - cell.com
Summary Background Since early 2022, Omicron BA. 1 has been eclipsed by BA. 2, which
was in turn outcompeted by BA. 5, which displays enhanced antibody escape properties …

Structural insights for neutralization of Omicron variants BA. 1, BA. 2, BA. 4, and BA. 5 by a broadly neutralizing SARS-CoV-2 antibody

S Kumar, A Patel, L Lai, C Chakravarthy… - Science …, 2022 - science.org
In this study, by characterizing several human monoclonal antibodies (mAbs) isolated from
single B cells of the COVID-19–recovered individuals in India who experienced ancestral …

SARS-CoV-2 variant Omicron: currently the most complete “escapee” from neutralization by antibodies and vaccines

M Li, F Lou, H Fan - Signal Transduction and Targeted Therapy, 2022 - nature.com
On December 23, 2021, five groups published their research results of clinical-approved
monoclonal antibodies, convalescent serum, and vaccine serum against B. 1.1. 529 …

Evolution of the SARS‐CoV‐2 omicron variants BA. 1 to BA. 5: implications for immune escape and transmission

LB Shrestha, C Foster, W Rawlinson… - Reviews in Medical …, 2022 - Wiley Online Library
The first dominant SARS‐CoV‐2 Omicron variant BA. 1 harbours 35 mutations in its Spike
protein from the original SARS‐CoV‐2 variant that emerged late 2019. Soon after its …

SARS-CoV-2 variant B. 1.617 is resistant to bamlanivimab and evades antibodies induced by infection and vaccination

M Hoffmann, H Hofmann-Winkler, N Krüger, A Kempf… - Cell reports, 2021 - cell.com
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants
threatens efforts to contain the coronavirus disease 2019 (COVID-19) pandemic. The …

B. 1.1. 529 escapes the majority of SARS-CoV-2 neutralizing antibodies of diverse epitopes

Y Cao, J Wang, F Jian, T Xiao, W Song, A Yisimayi… - BioRxiv, 2021 - biorxiv.org
Abstract The SARS-CoV-2 B. 1.1. 529 variant (Omicron) contains 15 mutations on the
receptor-binding domain (RBD). How Omicron would evade RBD neutralizing antibodies …

Comparative neutralisation profile of SARS-CoV-2 omicron subvariants BA. 2.75 and BA. 5

CW Tan, BL Lim, BE Young, AYY Yeoh, CF Yung… - The Lancet …, 2022 - thelancet.com
Despite an overall improvement in neutralising antibody titres following mRNA booster
vaccination or an omicron breakthrough infection (appendix p 5), there was a significant loss …

Antigenic sin of wild-type SARS-CoV-2 vaccine shapes poor cross-neutralization of BA. 4/5/2.75 subvariants in BA. 2 breakthrough infections

B Ju, Q Fan, M Wang, X Liao, H Guo, H Wang… - Nature …, 2022 - nature.com
Abstract With declining SARS-CoV-2-specific antibody titers and increasing numbers of
spike mutations, the ongoing emergence of Omicron subvariants causes serious challenges …