Molecular docking, and anti-biofilm activity of gold-complexed sulfonamides on Pseudomonas aeruginosa

CR Mizdal, ST Stefanello, PA Nogara, FAA Soares… - Microbial …, 2018 - Elsevier
The antibacterial activity of sulfadiazine Au-PPh 3, sulfadiazine Ph 2 P-Au-Au-PPh 2,
sulfamethoxazole Au-PPh 3, sulfamethoxazole Ph 2 P-Au-Au-PPh 2, sulfamethoxazole Au …

Molecular docking, quorum quenching effect, antibiofilm activity and safety profile of silver-complexed sulfonamide on Pseudomonas aeruginosa

FS Siqueira, CFS Alves, AK Machado, JD Siqueira… - Biofouling, 2021 - Taylor & Francis
Microbial infections caused by sessile microorganisms are known to be a more challenging
issue than infections caused by the same microorganisms in the planktonic state …

Synthesis, Molecular Docking, and Biofilm Formation Inhibitory Activity of 5‐Substituted 3,4‐Dihalo‐5H‐furan‐2‐one Derivatives on Pseudomonas aeruginosa

GY Liu, BQ Guo, WN Chen, C Cheng… - Chemical Biology & …, 2012 - Wiley Online Library
Pseudomonas aeruginosa (P. aeruginosa) colonize on most wounds and live as biofilm,
which causes antibiotic resistance and wounds unhealed. To investigate the effects of 5 …

Evaluation of the antibacterial and investigation of the molecular docking of new derivatives of 1, 3, 4-oxadiazole as inhibitors of quorum sensing system in the human …

S Ghameshlouei, NZ Ahrabi, A Souldozi… - Avicenna Journal of …, 2021 - ajcmi.umsha.ac.ir
Background: Oxadiazoles are a group of anti-inflammatory compounds that have a wide
range of activity due to their higher efficacy. Pseudomonas aeruginosa is an opportunistic …

The antibacterial and anti-biofilm activity of gold-complexed sulfonamides against methicillin-resistant Staphylococcus aureus

CR Mizdal, ST Stefanello, V da Costa Flores… - Microbial …, 2018 - Elsevier
The drug-resistant strains of Staphylococcus aureus have been considered as one of the
serious health threats, which are related to high patient hospitalization rates. Besides …

Molecular docking and biological evaluation of novel urea-tailed mannich base against Pseudomonas aeruginosa

SK Mohanvel, V Ravichandran, C Kamalanathan… - Microbial …, 2019 - Elsevier
Emergence of multi-drug resistant bacterial pathogens is escalating and it is essential to
develop novel strategies to combat these super bugs. LasR is a regulator switch that plays a …

Inhibition of biofilm and virulence properties of Pseudomonas aeruginosa by sub-inhibitory concentrations of aminoglycosides

F Khan, JW Lee, A Javaid, SK Park, YM Kim - Microbial Pathogenesis, 2020 - Elsevier
Aminoglycosides are a commonly used class of antibiotics; however, their application has
been discontinued due to the emergence of multi-drug resistance bacterial strains. In the …

Virtual Screening of FDA-Approved Drugs against LasR of Pseudomonas aeruginosa for Antibiofilm Potential

S Sadiq, NF Rana, MA Zahid, MK Zargaham… - Molecules, 2020 - mdpi.com
Pseudomonas aeruginosa is a Gram-negative pathogenic bacterium that is present
commonly in soil and water and is responsible for causing septic shock, pneumonia, urinary …

Effect of Silver Nanoparticles Against the Formation of Biofilm by Pseudomonas aeruginosa an In silico Approach

SS Vyshnava, DK Kanderi, SP Panjala… - Applied biochemistry …, 2016 - Springer
Studies were undertaken to examine the mechanism of mediation of silver nanoparticles in
inhibiting biofilm formation by Pseudomonas aeruginosa through LuxI/LuxR system of signal …

Antiquorum sensing activity of silver nanoparticles in P. aeruginosa: an in silico study

SG Ali, MA Ansari, QM Sajid Jamal, HM Khan… - In Silico …, 2017 - Springer
Pseudomonas aeruginosa an opportunistic pathogen regulates its virulence through
Quorum sensing (QS) mechanism comprising of Las and Rhl system. Targeting of QS …