Drug repositioning: Progress and challenges in drug discovery for various diseases

Y Hua, X Dai, Y Xu, G Xing, H Liu, T Lu, Y Chen… - European Journal of …, 2022 - Elsevier
Compared with traditional de novo drug discovery, drug repurposing has become an
attractive drug discovery strategy due to its low-cost and high efficiency. Through a …

[HTML][HTML] Network bioinformatics analysis provides insight into drug repurposing for COVID-19

X Li, J Yu, Z Zhang, J Ren, AE Peluffo, W Zhang… - Medicine in Drug …, 2021 - Elsevier
The COVID-19 disease caused by the SARS-CoV-2 virus is a health crisis worldwide. While
developing novel drugs and vaccines is long, repurposing existing drugs against COVID-19 …

[HTML][HTML] In silico drug repurposing carvedilol and its metabolites against SARS-CoV-2 infection using molecular docking and molecular dynamic simulation …

C Zhang, J Liu, Y Sui, S Liu, M Yang - Scientific Reports, 2023 - nature.com
The pandemic of coronavirus disease 2019 (COVID-19) caused by the infection of severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a significant impact on …

In silico Drug Repurposing for COVID‐19: Targeting SARS‐CoV‐2 Proteins through Docking and Consensus Ranking

CN Cavasotto, JI Di Filippo - Molecular informatics, 2021 - Wiley Online Library
In December 2019, an infectious disease caused by the coronavirus SARS‐CoV‐2
appeared in Wuhan, China. This disease (COVID‐19) spread rapidly worldwide, and on …

Fast identification of possible drug treatment of coronavirus disease-19 (COVID-19) through computational drug repurposing study

J Wang - Journal of chemical information and modeling, 2020 - ACS Publications
The recent outbreak of novel coronavirus disease-19 (COVID-19) calls for and welcomes
possible treatment strategies using drugs on the market. It is very efficient to apply computer …

Repurposing cefuroxime for treatment of COVID-19: a scoping review of in silico studies

AB Durojaiye, JRD Clarke… - Journal of …, 2021 - Taylor & Francis
Abstract Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), the causative
agent of Coronavirus disease 19 (COVID-19), is a novel human Coronavirus that is …

Vaccine development and therapeutic design for 2019‐nCoV/SARS‐CoV‐2: Challenges and chances

M Ghaebi, A Osali, H Valizadeh… - Journal of cellular …, 2020 - Wiley Online Library
The ongoing outbreak of the recently emerged 2019 novel coronavirus (nCoV), which has
seriously threatened global health security, is caused by severe acute respiratory syndrome …