The role of NO in COVID-19 and potential therapeutic strategies

W Fang, J Jiang, L Su, T Shu, H Liu, S Lai… - Free radical biology and …, 2021 - Elsevier
Nitric oxide (NO) is a free radical playing an important pathophysiological role in
cardiovascular and immune systems. Recent studies reported that NO levels were …

Serum nitrite and nitrate: A potential biomarker for post-covid-19 complications?

J Wang, F Mei, L Bai, S Zhou, D Liu, L Yao… - Free Radical Biology …, 2021 - Elsevier
Nitric oxide (NO) plays an important role in cardiovascular and immune systems.
Quantification of blood nitrite and nitrate, two relatively stable metabolites of NO (generally …

Nitric oxide to fight viral infections

F Lisi, AN Zelikin, R Chandrawati - Advanced Science, 2021 - Wiley Online Library
Abstract Coronavirus disease 2019 (COVID‐19) is an infectious disease caused by the
severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2) that has quickly and …

Implications of SARS-Cov-2 infection on eNOS and iNOS activity: Consequences for the respiratory and vascular systems

LMF Guimarães, CVT Rossini, C Lameu - Nitric oxide, 2021 - Elsevier
Symptoms of COVID-19 range from asymptomatic/mild symptoms to severe illness and
death, consequence of an excessive inflammatory process triggered by SARS-CoV-2 …

[HTML][HTML] Nitric oxide (NO) and nanoparticles–potential small tools for the war against COVID-19 and other human coronavirus infections

JC Pieretti, O Rubilar, RB Weller, GR Tortella… - Virus research, 2021 - Elsevier
The endogenous free radical nitric oxide (NO) plays a pivotal role in the immunological
system. NO has already been reported as a potential candidate for use in the treatment of …

Nitric oxide as a therapeutic option for COVID-19 treatment: a concise perspective

JM Mir, RC Maurya - New Journal of Chemistry, 2021 - pubs.rsc.org
In the prevailing coronavirus disease-2019 (COVID-19) times, scientists are eager to
develop vaccines against COVID-19, and careful measures are being taken to develop an …

Harnessing nitric oxide for preventing, limiting and treating the severe pulmonary consequences of COVID-19

NC Adusumilli, D Zhang, JM Friedman, AJ Friedman - Nitric oxide, 2020 - Elsevier
The ongoing outbreak of COVID-19 has quickly become a daunting challenge to global
health. In the absence of targeted therapy and a reported 5.5% case fatality rate in the …

Covid-19 accelerates endothelial dysfunction and nitric oxide deficiency

SJ Green - Microbes and infection, 2020 - ncbi.nlm.nih.gov
Martel and colleagues provide a thoughtful review on strategies to increase airway nitric
oxide to treat and possibly prevent Covid-19 [1]. However, it is becoming apparent that the …

[HTML][HTML] Mitigation of the replication of SARS-CoV-2 by nitric oxide in vitro

D Akaberi, J Krambrich, J Ling, C Luni, G Hedenstierna… - Redox biology, 2020 - Elsevier
The ongoing SARS-CoV-2 pandemic is a global public health emergency posing a high
burden on nations' health care systems and economies. Despite the great effort put in the …

[HTML][HTML] Decreased availability of nitric oxide and hydrogen sulfide is a hallmark of COVID-19

P Dominic, J Ahmad, R Bhandari, S Pardue… - Redox biology, 2021 - Elsevier
Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is involved in
a global outbreak affecting millions of people who manifest a variety of symptoms …