Background Uveal melanoma (UM) represents the most common primary intra-ocular malignancy in adults. Up to 50% of the patients develop distant metastases within 10 years …
S Sun, B Guo, L Xu, R Shi - BMC cancer, 2022 - Springer
Background Uveal melanoma (UM) is the most common primary intraocular malignancy with a strong tendency to metastasize. The prognosis is poor once metastasis occurs. The …
Y Qin, K Bollin, MP De MacEdo… - … for immunotherapy of …, 2020 - ncbi.nlm.nih.gov
Background To date, no systemic therapy, including immunotherapy, exists to improve clinical outcomes in metastatic uveal melanoma (UM) patients. To understand the role of …
S Chen, Z Tang, Q Wan, W Huang, X Li, X Huang… - Cancer Cell …, 2024 - Springer
Purpose Uveal melanoma (UM) is adults' most common primary intraocular malignant tumor. It has been observed that 40% of patients experience distant metastasis during subsequent …
M Lachota, A Lennikov, KJ Malmberg… - Journal of …, 2021 - Wiley Online Library
Tumor‐infiltrating immune cells are capable of effective cancer surveillance, and their abundance is linked to better prognosis in numerous tumor types. However, in uveal …
T Meir, R Dror, X Yu, J Qian, I Simon… - … & visual science, 2007 - arvojournals.org
purpose. The liver is the most common site of systemic metastases from uveal melanoma (UM). Such metastases usually continue to develop despite the application of current …
S Meng, T Zhu, Z Fan, Y Cheng, Y Dong… - Frontiers in …, 2023 - frontiersin.org
Background: Uveal melanoma (UM) is the most frequent ocular neoplasm with a strong metastatic ability. The prognostic value of metastasis-associated genes (MAGs) of UM …
H Pan, L Lu, J Cui, Y Yang, Z Wang, X Fan - Aging (Albany NY), 2020 - ncbi.nlm.nih.gov
Uveal melanoma is an aggressive intraocular malignancy that often exhibits low immunogenicity. Metastatic uveal melanoma samples frequently exhibit monosomy 3 or …
GF Jang, JS Crabb, B Hu, B Willard, H Kalirai… - Cancers, 2021 - mdpi.com
Simple Summary This study pursued the proteomic analysis of primary uveal melanoma (pUM) for insights into the mechanisms of metastasis and protein biomarkers. Liquid …