Although reperfusion is essential in restoring circulation to ischemic myocardium, it also
leads to irreversible events including reperfusion injury, decreased cardiac function and …

Reperfusion therapy is commonly applied after a myocardial infarction. Reperfusion,
however, causes secondary damage. An emerging approach for treatment of ischemia …

Herein we investigated a new strategy for the modulation of cardiac macrophages to a
reparative state, at a predetermined time after myocardial infarction (MI), in aim to promote …

ATP cannot be effectively delivered to most tissues including the ischemic myocardium
without protection from degradation by plasma endonucleotidases. However, it has been …

Induction of cardiac muscle regeneration following myocardial infarction (MI) represents a
major challenge in cardiovascular therapy, as the current clinical approaches are limited in …

A major obstacle to drug therapy for treatment of potential myocardial infarction is the limited
access to the ischemic myocardium by drugs in an active form. Encouraging results have …

Adverse cardiac remodeling after myocardial infarction ultimately causes heart failure. To
stimulate reparative processes in the infarct, efficient delivery and retention of therapeutic …

Cardiovascular disease processes such as atherosclerosis, restenosis, and inflammation
are typically localized to discrete regions of the vasculature, affording great opportunity for …

Immunoliposome (IL) targeting to areas of inflammation after an acute myocardial infarction
(MI) could provide the means by which pro‐angiogenic compounds can be selectively …

Ischemic cardiac disease (ICD) is a cardiovascular disease with high morbidity and
mortality. In this study, a novel myocardial targeted drug delivery system was developed …