G protein-coupled receptors (GPCRs), the largest family of human membrane proteins and
an important class of drug targets, play a role in maintaining numerous physiological …

As one of the most successful therapeutic target families, G protein-coupled receptors
(GPCRs) have experienced a transformation from random ligand screening to knowledge …

G-protein coupled receptors (GPCRs) comprise the largest family of proteins in our body,
which have many important physiological functions and are implicated in the …

Their ubiquitous nature, wide cellular distribution and versatile molecular recognition and
signalling help make G-protein binding receptors (GPCRs) the most important class of …

Heterotrimeric G-protein-coupled receptors (GPCRs) represent a large protein family
responsible for mediating extracellular to intracellular signaling within a broad range of …

G protein-coupled receptors (GPCRs) are critical regulators of human physiology and make
up the largest single class of therapeutic drug targets. Although GPCRs regulate highly …

G protein-coupled receptors (GPCRs) are the largest family of cell signaling transmembrane
proteins that can be modulated by a plethora of chemical compounds. Systematic …

The great versatility of G protein-coupled receptors (GPCRs), in terms of both their ability to
bind different types of ligands and initiate a large number of distinct cellular signaling events …

G protein-coupled receptors (GPCRs) are known to interact with several other classes of
integral membrane proteins that modulate their biology and pharmacology. However, the …

During the past few years, crystallography of G protein–coupled receptors (GPCRs) has
experienced exponential growth, resulting in the determination of the structures of 16 distinct …