With recent studies suggesting a key role for professional antigen presenting cells in the
induction of major histocompatibility class I cellular immune responses, we initiated studies …

The transporter associated with antigen processing (TAP) plays a key role in adaptive
immunity by translocating proteasomal degradation products from the cytosol into the …

The heterodimeric peptide transporter associated with antigen processing (TAP) consisting
of the subunits TAP1 and TAP2 mediates the transport of cytosolic peptides into the lumen of …

Transporter in Ag processing-1 (TAP-1, previously called PSF-1 or Ring-4) is an MHC-
encoded gene product that is required for efficient association of intracellular peptide Ag …

Macrophage motility is crucial in innate immunity. Toll-like receptors (TLRs), members of the
interleukin-1 receptor superfamily, are a family of transmembrane pattern recognition …

Abstract Signal-transducing adaptor protein-2 (STAP-2) is a recently identified adaptor
protein that contains pleckstrin and Src homology 2-like domains as well as a YXXQ motif in …

Recently, four genes (TAP1, TAP2, LMP2, LMP7) involved or potentially involved in the
processing and transport of major histocompatibility complex class I-associated antigen to …

Solute carrier family 11 member a1 (Slc11a1; formerly Nramp1) encodes a late
endosomal/lysosomal protein/divalent cation transporter that regulates iron homeostasis in …

Complete activation of macrophages during immune responses results from stimulation with
the activating cytokine interferon‐γ (IFN‐γ) and a second stimulus, usually a microbial …

Constitutive activation of signal transducer and activator of transcription 1 (STAT1) is a
distinctive feature of Epstein-Barr virus (EBV)-immortalized B cells (lymphoblastoid cell lines …