Results The pooled estimate risk ratio (RR) of omega-6 PUFA supplementation was 0.94 for
any CVD event (95% CI: 0.77–1.15, I 2= 66.2%), 1.06 for CVD death (95% CI: 0.73–1.55, I …

The omega-3 fatty acids (FA) found in fish oils, eicosapentaenoic and docosahexaenoic
acids (EPA and DHA, respectively), have been extensively studied therapeutically in a wide …

The high-fat diet of North Americans has a major impact on cardiovascular disease
occurrence. Notably, fatty acids have been identified as important factors that could …

Interest in the potential cardiovascular (CV) benefits of omega-3 polyunsaturated fatty acids
(Ω-3) began in the 1940s and was amplified by a subsequent landmark trial showing …

Abstract The 2015 Dietary Guidelines for Americans recommend limiting the intake of
saturated fatty acids (SFAs) to< 10% of energy/d and replacing dietary SFAs with …

Given the notorious impact of cardiovascular disease (CVD) as the current leading cause of
mortality worldwide, the prevention, identification and management of CV risk factors …

Abstract Omega-3 fatty acids (O3FAs) possess beneficial properties for cardiovascular (CV)
health and elevated O3FA levels are associated with lower incident risk for CV disease …

In cardiology, results of recent large intervention trials with eicosapentaenoic acid (EPA)
plus docosahexaenoic acid (DHA) supplements were neutral. In contrast, in epidemiologic …

Multiple randomized controlled trials (RCTs) have assessed the effects of supplementation
with eicosapentaenoic acid plus docosahexaenoic acid (omega-3 polyunsaturated fatty …

Abstract Purpose of Review Omega-3 fatty acids (n-3 FA) lower triglycerides, have anti-
inflammatory properties, and improve metabolism. Clinical evidence of cardiovascular …