[HTML][HTML] The prevalence and outcomes of frailty in older cancer patients: a systematic review

C Handforth, A Clegg, C Young, S Simpkins… - Annals of oncology, 2015 - Elsevier
Background Frailty is a state of vulnerability to poor resolution of homeostasis following a
stressor event, such as chemotherapy or cancer surgery. Better knowledge of the …

Frailty and cancer: implications for oncology surgery, medical oncology, and radiation oncology

CG Ethun, MA Bilen, AB Jani, SK Maithel… - CA: a cancer journal …, 2017 - Wiley Online Library
Answer questions and earn CME/CNE The concept of frailty has become increasingly
recognized as one of the most important issues in health care and health outcomes and is of …

How should older adults with cancer be evaluated for frailty?

M Huisingh-Scheetz, J Walston - Journal of geriatric oncology, 2017 - Elsevier
Traditionally used as a descriptive term, frailty is now a recognized medical syndrome
identifying individuals with decreased physiologic reserve. Frailty is characterized by …

Geriatric assessment is superior to oncologists' clinical judgement in identifying frailty

L Kirkhus, J Šaltytė Benth, S Rostoft… - British journal of …, 2017 - nature.com
Background: Frailty is a syndrome associated with increased vulnerability and an important
predictor of outcomes in older cancer patients. Systematic assessments to identify frailty are …

Frailty and cancer: current perspectives on assessment and monitoring

V Goede - Clinical interventions in aging, 2023 - Taylor & Francis
Frailty, an age-related condition of increased vulnerability to acute endogenous or
exogenous stressors, is a key barrier to successful treatment of cancer in older people. In …

Frailty index developed from a cancer-specific geriatric assessment and the association with mortality among older adults with cancer

EJ Guerard, AM Deal, YK Chang, GR Williams… - Journal of the National …, 2017 - jnccn.org
Background: An objective measure is needed to identify frail older adults with cancer who
are at increased risk for poor health outcomes. The primary objective of this study was to …

The frailty syndrome: a critical issue in geriatric oncology

L Ferrucci, JM Guralnik, C Cavazzini… - Critical reviews in …, 2003 - Elsevier
Evidence exists that the geriatric intervention guided by Comprehensive Geriatric
Assessment (CGA) has positive effects on a number of important health outcomes in frail …

Performance of four frailty classifications in older patients with cancer: prospective elderly cancer patients cohort study

E Ferrat, E Paillaud, P Caillet, M Laurent… - Journal of Clinical …, 2017 - ascopubs.org
Purpose Frailty classifications of older patients with cancer have been developed to assist
physicians in selecting cancer treatments and geriatric interventions. They have not been …

The association of frailty with outcomes after cancer surgery: a systematic review and metaanalysis

JF Shaw, D Budiansky, F Sharif, DI McIsaac - Annals of Surgical Oncology, 2022 - Springer
Background Cancer is common in older adults, who often have concurrent frailty. Frailty is a
strong predictor of adverse outcomes in surgical patients. Our objective is to systematically …

Cancer in the frail patient: a coming epidemic

L Balducci, G Stanta - Hematology/oncology clinics of North America, 2000 - Elsevier
Aging is associated with a progressive decline in the functional reserve of many organ
systems, 22 and this functional restriction can compromise the tolerance of stress, including …