A review of specific dietary antioxidants and the effects on biochemical mechanisms related to neurodegenerative processes

E Esposito, D Rotilio, V Di Matteo, C Di Giulio… - Neurobiology of …, 2002 - Elsevier
Aging is a major risk factor for neurodegenerative diseases including Alzheimer's disease
(AD), Parkinson's disease (PD), and amyotrophic lateral sclerosis (ALS). An unbalanced …

Antioxidant neuroprotection in Alzheimer's disease as preventive and therapeutic approach

C Behl, B Moosmann - Free Radical Biology and Medicine, 2002 - Elsevier
Various neurodegenerative disorders and syndromes are associated with oxidative stress.
The deleterious consequences of excessive oxidations and the pathophysiological role of …

Recent updates in the treatment of neurodegenerative disorders using natural compounds

M Rasool, A Malik, MS Qureshi… - Evidence‐Based …, 2014 - Wiley Online Library
Neurodegenerative diseases are characterized by protein aggregates and inflammation as
well as oxidative stress in the central nervous system (CNS). Multiple biological processes …

Neurodegenerative diseases: from available treatments to prospective herbal therapy

I Solanki, P Parihar, MS Parihar - Neurochemistry international, 2016 - Elsevier
Neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease and many
others represent a relevant health problem with age worldwide. Efforts have been made in …

Oxidative stress, antioxidants and neurodegenerative diseases

I Casetta, V Govoni, E Granieri - Current pharmaceutical design, 2005 - ingentaconnect.com
It is widely accepted that oxidative stress increases with age, and that age is a major risk
factor for several neurodegenerative diseases such as Parkinson's disease and Alzheimer's …

Protective mechanisms of flavonoids in Parkinson's disease

KB Magalingam, AK Radhakrishnan… - Oxidative medicine …, 2015 - Wiley Online Library
Parkinson's disease is a chronic, debilitating neurodegenerative movement disorder
characterized by progressive degeneration of dopaminergic neurons in the substantia nigra …

Therapeutic potential of polyphenols in amyotrophic lateral sclerosis and frontotemporal dementia

V Novak, B Rogelj, V Župunski - Antioxidants, 2021 - mdpi.com
Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are severe
neurodegenerative disorders that belong to a common disease spectrum. The molecular …

Merging the multi-target effects of phytochemicals in neurodegeneration: From oxidative stress to protein aggregation and inflammation

F Limanaqi, F Biagioni, F Mastroiacovo, M Polzella… - Antioxidants, 2020 - mdpi.com
Wide experimental evidence has been provided in the last decade concerning the
neuroprotective effects of phytochemicals in a variety of neurodegenerative disorders …

Considerations for the use of polyphenols as therapies in neurodegenerative diseases

J Renaud, MG Martinoli - International Journal of Molecular Sciences, 2019 - mdpi.com
Over the last two decades, the increase in the incidence of neurodegenerative diseases due
to the increasingly ageing population has resulted in a major social and economic burden …

Anti-inflammatory effects of flavonoids in neurodegenerative disorders

C Spagnuolo, S Moccia, GL Russo - European journal of medicinal …, 2018 - Elsevier
Neuroinflammation is one of the main mechanisms involved in the progression of several
neurodegenerative diseases, such as Parkinson, Alzheimer, multiple sclerosis, amyotrophic …