The B cell response to different pathogens uses tailored effector mechanisms and results in
functionally specialized memory B (Bm) cell subsets, including CD21+ resting, CD21 …

Memory B cells play a fundamental role in host defenses against viruses, but to date, their
role has been relatively unsettled in the context of SARS-CoV-2. We report here a …

Memory B cells seem to be more durable than antibodies and thus crucial for the long-term
immunity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection …

Although both infections and vaccines induce memory B cell (MBC) populations that
participate in secondary immune responses, the MBCs generated in each case can differ …

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), the causative agent of the
pandemic human respiratory illness COVID-19, is a global health emergency. While severe …

Robust population-wide immunity will help to curb the SARS-CoV-2 pandemics. To maintain
the immunity at protective levels, the quality and persistence of the immune response …

Protective immunity against COVID-19 likely depends on the production of SARS-CoV-2–
specific plasma cells and memory B cells postinfection or postvaccination. Previous work …

Memory B cells are comprised of unswitched (CD27+ IgD+) and switched (CD27+ IgD-)
subsets. The origin and function of unswitched human memory B cells are debated in the …

Memory B cells (MBCs) generate rapid antibody responses upon secondary encounter with
a pathogen. Here, we investigated the kinetics, avidity, and cross-reactivity of serum …

Multiple studies have shown loss of severe acute respiratory syndrome coronavirus 2–
specific (SARS-CoV-2–specific) antibodies over time after infection, raising concern that …