[HTML][HTML] Development of finely tuned liposome nanoplatform for macrophage depletion

TH Choi, RJ Yoo, JY Park, JY Kim, YC Ann… - Journal of …, 2024 - Springer
Background Immunotherapy with clodronate-encapsulated liposomes, which induce
macrophage depletion, has been studied extensively. However, previously reported …

Beyond trial and error: a systematic development of liposomes targeting primary macrophages

F Weber, DC Ivan, ST Proulx, G Locatelli… - Advanced …, 2021 - Wiley Online Library
Monocytes/macrophages are phagocytic innate immune cells playing a pivotal role in tissue
homeostasis, inflammation, and antitumor immunity in a microenvironment‐dependent …

Albumin coated liposomes: a novel platform for macrophage specific drug delivery

C Vuarchey, S Kumar, R Schwendener - Nanotechnology …, 2011 - pagepress.org
Here we report a new and efficient approach of macrophage specific drug delivery by
coating liposomes with albumin. Activated albumin was reacted with liposomes containing …

Drug-free mannosylated liposomes inhibit tumor growth by promoting the polarization of tumor-associated macrophages

J Ye, Y Yang, W Dong, Y Gao, Y Meng… - International journal …, 2019 - Taylor & Francis
Background: Tumor-associated macrophages (TAMs) are critical in tumor progression and
metastasis. Selective targeting of TAMs holds great potential to ameliorate the …

Multifunctional liposomes remodeling tumor immune microenvironment for tumor chemoimmunotherapy

X Li, Y Luo, Z Huang, Y Wang, J Wu, S Zhou - Small Methods, 2023 - Wiley Online Library
In the treatment of solid tumors, the complex barriers composed of cancer‐associated
fibroblasts (CAFs) prevent drug delivery and T cells infiltration into tumor tissues. Although …

[HTML][HTML] Liposomes-Human phagocytes interplay in whole blood: effect of liposome design

M Giambelluca, E Markova, C Louet, B Steinkjer… - … , Biology and Medicine, 2023 - Elsevier
Nanomedicine holds immense potential for therapeutic manipulation of phagocytic immune
cells. However, in vitro studies often fail to accurately translate to the complex in vivo …

Liposomes for specific depletion of macrophages from organs and tissues

N Van Rooijen, E Hendrikx - Liposomes: Methods and protocols, volume 1 …, 2010 - Springer
A liposome mediated macrophage “suicide” approach has been developed, based on the
liposome mediated internalization of the small hydrophilic molecule clodronate in …

Engineered Liposomes for Drug Delivery and Biomedical Imaging

K Sou - Recent Patents on Nanomedicine, 2014 - ingentaconnect.com
Nanoparticles are widely used as carrier materials for biomedical applications such as
functional and morphological imaging diagnosis and therapeutic drug delivery. Based on …

Mechanisms of selective monocyte targeting by liposomes functionalized with a cationic, arginine-rich lipopeptide

R Münter, M Bak, E Christensen, PJ Kempen… - Acta Biomaterialia, 2022 - Elsevier
Stimulation of monocytes with immunomodulating agents can harness the immune system to
treat a long range of diseases, including cancers, infections and autoimmune diseases. To …

[HTML][HTML] Liposomes trigger bone marrow niche macrophage “foam” cell formation and affect hematopoiesis in mice

Y Li, R Yao, M Ren, K Yuan, Y Du, Y He, H Kang… - Journal of Lipid …, 2022 - ASBMB
Liposomes are the most widely used nanocarrier platform for the delivery of therapeutic and
diagnostic agents, and a number of liposomes have been approved for use in clinical …