COVID‐19 is frequently accompanied by a hypercoagulable inflammatory state with
microangiopathic pulmonary changes that can precede the diffuse alveolar damage …

In a stunningly short period of time, the unexpected coronavirus disease 2019 (COVID-19)
pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS–CoV-2), has …

Hyperactivation of the complement and coagulation systems is recognized as part of the
clinical syndrome of COVID-19. Here we review systemic complement activation and local …

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) may manifest as
thrombosis, stroke, renal failure, myocardial infarction, and thrombocytopenia, reminiscent of …

The complement system is an essential component of the innate immune system. The three
complement pathways (classical, lectin, alternative) are directly or indirectly activated by the …

Abstract Coronavirus disease of 2019 (COVID-19) is a highly contagious respiratory
infection that is caused by the severe acute respiratory syndrome coronavirus 2. Although …

Acute respiratory failure and a systemic coagulopathy are critical aspects of the morbidity
and mortality characterizing infection with severe acute respiratory distress syndrome …

COVID‐19 is a complex disease manifesting in a broad severity spectrum and involving
distinct organs and systems. Hyperinflammation, including complement over‐activation, has …

In December 2019, the world was introduced to a new betacoronavirus, referred to as
severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) for its propensity to cause …

Increasing evidence suggests that activation of the complement system plays a key role in
the pathogenesis and disease severity of Coronavirus disease 2019 (COVID-19). We used a …