Airways expression of SARS-CoV-2 receptor, ACE2, and TMPRSS2 is lower in children than adults and increases with smoking and COPD

NS Sharif-Askari, FS Sharif-Askari, M Alabed… - … Therapy Methods & …, 2020 - cell.com
It has been reported that angiotensin-converting enzyme 2 (ACE2) and transmembrane
serine protease 2 (TMPRSS2) are the main cell entry proteins for severe acute respiratory …

Considerations in treating patients with advance lung cancer during the epidemic outbreak of novel coronavirus (SARS-CoV-2)

Y Cai, Y Xu, D Xu, Y Wang, X Wang, C Sun, Y Guo… - Medical Oncology, 2020 - Springer
The outbreak of pneumonia caused by novel coronavirus (SARS-CoV-2) in Wuhan, China,
at the end of 2019 quickly escalated into a global health emergency. Since its outbreak until …

[HTML][HTML] Discovery of the Retinol STRA6 Receptor as a Novel Binding Receptor for SARS-CoV-2 in COVID-19: In Silico Research.

MR Elkazzaz, T Haydara, YE Abo-Amer, H Sahyon… - 2021 - europepmc.org
Background: The COVID-19 pandemic caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) has infected over 100 million people causing over 2.4 million …

Exploring the potential mechanism of emetine against coronavirus disease 2019 combined with lung adenocarcinoma: bioinformatics and molecular simulation …

K Zhang, K Wang, C Zhang, X Teng, D Li, M Chen - BMC cancer, 2022 - Springer
Background Patients with lung adenocarcinoma (LUAD) may be more predisposed to
coronavirus disease 2019 (COVID-19) and have a poorer prognosis. Currently, there is still …

Dealing with lung cancer in the COVID‑19 scenario (A review)

V Aran, P De Marchi, M Zamboni… - Molecular and …, 2021 - spandidos-publications.com
The severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2), which has caused the
coronavirus disease 2019 (COVID‑19), first appeared in December 2019 in Wuhan (China) …

Expression of SARS-CoV-2 host cell entry factors in immune system components of healthy individuals and its relevance for COVID-19 immunopathology

A Kumar, S Kumar, RK Narayan, C Kumari… - Viral …, 2021 - liebertpub.com
Intense immunological dysregulation including immune cell lesions has been
characteristically observed in severe cases of coronavirus disease-2019 (COVID-19), for …

Advanced bioinformatics rapidly identifies existing therapeutics for patients with coronavirus disease-2019 (COVID-19)

J Kim, J Zhang, Y Cha, S Kolitz, J Funt… - Journal of translational …, 2020 - Springer
Background The recent global pandemic has placed a high priority on identifying drugs to
prevent or lessen clinical infection of severe acute respiratory syndrome coronavirus 2 …

Development and Validation of Nomograms for Predicting Pneumonia in Patients with COVID-19 and Lung Cancer

Y Xu, H Li, X Wang, B Li, A Gao, Q Zhao… - Journal of …, 2024 - Taylor & Francis
Background COVID-19 has spread worldwide, becoming a global threat to public health and
can lead to complications, especially pneumonia, which can be life-threatening. However, in …

Thoughts on detecting tissue distribution of potential COVID-19 receptors

H Tang, X Lu, S Qie, J Xi - Future Virology, 2020 - Taylor & Francis
Aim: As a novel coronavirus, coronavirus disease 2019 (COVID-19) has caused a global
epidemic. Many clinical data show that COVID-19 can not only cause viral pneumonia but …

Identification of toll‐like receptor 5 and acyl‐CoA synthetase long chain family member 1 as hub genes are correlated with the severe forms of COVID‐19 by Weighted …

L Wang, Z Mao, F Shao - IET Systems Biology, 2023 - Wiley Online Library
Since a 25% mortality rate occurred in critical Coronavirus disease 2019 (COVID‐19)
patients, investigating the potential drivers remains to be important. Here, the authors …