J Andrews, G Guyatt, AD Oxman, P Alderson… - Journal of clinical …, 2013 - Elsevier
This article describes the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) approach to classifying the direction and strength of recommendations …
GRADE requires guideline developers to make an overall rating of confidence in estimates of effect (quality of evidence—high, moderate, low, or very low) for each important or critical …
Presenting continuous outcomes in Summary of Findings tables presents particular challenges to interpretation. When each study uses the same outcome measure, and the …
Direct evidence comes from research that directly compares the interventions in which we are interested when applied to the populations in which we are interested and measures …
This article is the first of a series providing guidance for use of the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) system of rating …
M Brunetti, I Shemilt, S Pregno, L Vale… - Journal of clinical …, 2013 - Elsevier
OBJECTIVES: In this article, we describe how to include considerations about resource utilization when making recommendations according to the Grading of Recommendations …
GH Guyatt, AD Oxman, R Kunz, D Atkins… - Journal of clinical …, 2011 - Elsevier
GRADE requires a clear specification of the relevant setting, population, intervention, and comparator. It also requires specification of all important outcomes—whether evidence from …
This article deals with inconsistency of relative (rather than absolute) treatment effects in binary/dichotomous outcomes. A body of evidence is not rated up in quality if studies yield …
This article introduces the approach of GRADE to rating quality of evidence. GRADE specifies four categories—high, moderate, low, and very low—that are applied to a body of …