Systematic Integration of Brain eQTL and GWAS Identifies ZNF323 as a Novel Schizophrenia Risk Gene and Suggests Recent Positive Selection …
Genome-wide association studies have identified multiple risk variants and loci that show
robust association with schizophrenia. Nevertheless, it remains unclear how these variants …
robust association with schizophrenia. Nevertheless, it remains unclear how these variants …
Schizophrenia genetics: progress, at last
JG Mulle - Current opinion in genetics & development, 2012 - Elsevier
The heritability of schizophrenia is well established, and has motivated the search for
genetic variation that contributes to susceptibility. Recent progress from both genome-wide …
genetic variation that contributes to susceptibility. Recent progress from both genome-wide …
Genetics of schizophrenia
I Escudero, M Johnstone - Current psychiatry reports, 2014 - Springer
The genetic basis of schizophrenia has been a hotly debated research topic for decades, yet
recent studies, especially in the past year, have confirmed genetics as the major cause of …
recent studies, especially in the past year, have confirmed genetics as the major cause of …
Polygenic risk scores shed light on the relationship between schizophrenia and cognitive functioning: review and meta-analysis
Schizophrenia is a multifactorial disease associated with widespread cognitive impairment.
Although cognitive deficits are one of the factors most strongly associated with functional …
Although cognitive deficits are one of the factors most strongly associated with functional …
A screen of 1,049 schizophrenia and 30 Alzheimer's‐associated variants for regulatory potential
Recent genome‐wide association studies (GWAS) identified numerous schizophrenia (SZ)
and Alzheimer's disease (AD) associated loci, most outside protein‐coding regions and …
and Alzheimer's disease (AD) associated loci, most outside protein‐coding regions and …
Genome‐Wide Findings in Schizophrenia and the Role of Gene–Environment Interplay
R Van Winkel, G Esquivel, G Kenis… - CNS neuroscience & …, 2010 - Wiley Online Library
The recent advent of genome‐wide mass‐marker technology has resulted in renewed
optimism to unravel the genetic architecture of psychotic disorders. Genome‐wide …
optimism to unravel the genetic architecture of psychotic disorders. Genome‐wide …
Pathogenic rare copy number variants in community-based schizophrenia suggest a potential role for clinical microarrays
Individually rare, large copy number variants (CNVs) contribute to genetic vulnerability for
schizophrenia. Unresolved questions remain, however, regarding the anticipated yield of …
schizophrenia. Unresolved questions remain, however, regarding the anticipated yield of …
Genome-wide linkage analyses of 12 endophenotypes for schizophrenia from the Consortium on the Genetics of Schizophrenia
Objective The Consortium on the Genetics of Schizophrenia has undertaken a large
multisite study to characterize 12 neurophysiological and neurocognitive endophenotypic …
multisite study to characterize 12 neurophysiological and neurocognitive endophenotypic …
Schizophrenia risk variants influence multiple classes of transcripts of sorting nexin 19 (SNX19)
Genome-wide association studies (GWAS) have identified many genomic loci associated
with risk for schizophrenia, but unambiguous identification of the relationship between …
with risk for schizophrenia, but unambiguous identification of the relationship between …
Uncovering the hidden risk architecture of the schizophrenias: confirmation in three independent genome-wide association studies
Objective: The authors sought to demonstrate that schizophrenia is a heterogeneous group
of heritable disorders caused by different genotypic networks that cause distinct clinical …
of heritable disorders caused by different genotypic networks that cause distinct clinical …