[引用][C] [P4–001]: MMFS TREATMENT AMELIORATES FRONTAL CORTEX DYSFUNCTION IN MILD‐MODERATE ALZHEIMER's DISEASE PATIENTS

JG Weinger, G Liu - Alzheimer's & Dementia, 2017 - Wiley Online Library
Background Alzheimer's Disease (AD) is a synaptic dysfunction disease; synaptic loss is the
best predictor of cognitive decline. Therefore, a compound that can increase synaptic …

[HTML][HTML] Regulation of structural and functional synapse density by L-threonate through modulation of intraneuronal magnesium concentration

Q Sun, JG Weinger, F Mao, G Liu - Neuropharmacology, 2016 - Elsevier
Oral administration of the combination of L-threonate (threonate) and magnesium (Mg 2+) in
the form of L-Threonic acid Magnesium salt (L-TAMS) can enhance learning and memory in …

Efficacy and safety of MMFS-01, a synapse density enhancer, for treating cognitive impairment in older adults: a randomized, double-blind, placebo-controlled trial

G Liu, JG Weinger, ZL Lu, F Xue… - Journal of Alzheimer's …, 2016 - content.iospress.com
Background: Cognitive impairment is a major problem in elderly, affecting quality of life. Pre-
clinical studies show that MMFS-01, a synapse density enhancer, is effective at reversing …

An 8-week open label trial of l-Threonic Acid Magnesium Salt in patients with mild to moderate dementia

TE Wroolie, K Chen, KT Watson, A Iagaru… - … Medicine in Psychiatry, 2017 - Elsevier
Emerging research on the effects of a novel magnesium compound of l-Threonic Acid
Magnesium Salt (l-TAMS) containing Vitamins C and D on cognitive performance suggests …

Effects of rTMS treatment on global cognitive function in Alzheimer's disease: A systematic review and meta-analysis

T Zhang, Y Sui, Q Lu, X Xu, Y Zhu, W Dai… - Frontiers in Aging …, 2022 - frontiersin.org
Background Although repetitive transcranial magnetic stimulation (rTMS) has been
extensively studied in patients with Alzheimer's disease (AD), the clinical evidence remains …

Short and long-term effects of rTMS treatment on Alzheimer's disease at different stages: a pilot study

G Rutherford, B Lithgow… - Journal of experimental …, 2015 - journals.sagepub.com
Repetitive transcranial magnetic stimulation (rTMS) uses a magnetic coil to induce an
electric field in brain tissue. As a pilot study, we investigated the effect of rTMS treatment on …

Effects of a newly developed cognitive intervention in amnestic mild cognitive impairment and mild Alzheimer's disease: a pilot study

VC Buschert, U Friese, SJ Teipel… - Journal of …, 2011 - content.iospress.com
Recent studies have shown that patients with Alzheimer's disease (AD) and its possible
prodromal stage mild cognitive impairment benefit from cognitive interventions. Few studies …

Does rTMS improve cognitive function in age‐related neurodegenerative diseases? A systematic review and meta‐analysis

A Miller, RJ Allen, AA Juma… - Alzheimer's & …, 2023 - Wiley Online Library
Background High‐frequency, repetitive transcranial magnetic stimulation (rTMS) targeted
over the dorsolateral prefrontal cortex (DLPFC) is widely used in research to promote …

PAS-MCI: Design and Rationale for a Randomized Controlled Trial to Enhance Prefrontal Cortical Plasticity and Working Memory in Individuals with Amnestic Mild …

F Genadry, N Ledwos, S Kumar, CR Bowie… - The American Journal of …, 2022 - Elsevier
Introduction Amnestic Mild Cognitive Impairment (aMCI) is a prodromal stage to Alzheimer's
disease dementia (AD). Improving prefrontal cortical function in individuals with MCI could …

[引用][C] O3‐07‐05: Long‐term effects of a multicomponent cognitive intervention in amnestic mild cognitive impairment (aMCI)

V Buschert, I Giegling, W Merensky, S Jolk… - Alzheimer's & …, 2011 - Wiley Online Library
Background Recent studies and a current randomized controlled trial on a mutlicomponent
cognitive intervention program demonstrated benefits through cognitive intervention in …