Alzheimer's disease (AD) is associated with aberrant neuronal activity, which is believed to
critically determine disease symptoms. How these activity alterations emerge, how stable …

Progressive cognitive decline in Alzheimer's disease could either be caused by a spreading
molecular pathology or by an initially focal pathology that causes aberrant neuronal activity …

Alzheimer's disease (AD) is characterized by progressive memory loss and cognitive
decline. These impairments correlate with early alterations in neuronal network activity in AD …

The accumulation of amyloid-β in the brain is an essential feature of Alzheimer's disease.
However, the impact of amyloid-β-accumulation on neuronal dysfunction on the single cell …

The effect of Alzheimer's disease pathology on activity of individual neocortical neurons in
the intact neural network remains obscure. Ongoing spontaneous activity, which constitutes …

Age-dependent accumulation of amyloid-β, provoking increasing brain amyloidopathy,
triggers abnormal patterns of neuron activity and circuit synchronization in Alzheimer's …

Alzheimer's disease (AD) is characterized by a progressive dysfunction of central neurons.
Recent experimental evidence indicates that in the cortex, in addition to the silencing of a …

Extracellular deposition of the amyloid-β peptide (Aβ) in the brain parenchyma is a hallmark
lesion of Alzheimer's disease (AD) and a predictive marker for the progression of preclinical …

Abstract β-amyloid is hypothesized to harm neural function and cognitive abilities by
perturbing synaptic transmission and plasticity in Alzheimer's disease (AD). To assess the …

Alzheimer's Disease (AD) is the most common form of dementia. The condition
predominantly affects the cerebral cortex and hippocampus and is characterized by the …