Vascular endothelial growth factor (VEGF) and its receptors

G Neufeld, T Cohen, S Gengrinovitch… - The FASEB …, 1999 - Wiley Online Library
Vascular endothelial growth factor (VEGF) is a highly specific mitogen for vascular
endothelial cells. Five VEGF isoforms are generated as a result of alternative splicing from a …

Signal transduction by vascular endothelial growth factor receptors

L Claesson-Welsh - Biochemical Society Transactions, 2003 - portlandpress.com
Vascular endothelial growth factor (VEGF)/vascular permeability factor is the prototype for a
growing family of dimeric growth factors, which exert their effects on vascular and lymphatic …

Vascular endothelial growth factor

N Ferrara - Trends in cardiovascular medicine, 1993 - Elsevier
An understanding of the mechanisms regulating growth and differentiation of vascular
endothelial cells is very important for cardiovascular biology and medicine. Several potential …

The vascular endothelial growth factor family and its receptors

AA Parikh, LM Ellis - Hematology/Oncology Clinics, 2004 - hemonc.theclinics.com
The dependence of tumor growth on the development of a neovasculature is well-
established [1]. After a tumor grows beyond 100 mm to 200 mm in size, diffusion alone is no …

Expression of vascular endothelial growth factor (VEGF) and VEGF receptors in tumor angiogenesis and malignancies

CR Pradeep, ES Sunila… - Integrative cancer …, 2005 - journals.sagepub.com
Angiogenesis is a process by which new blood vessels are formed from preexisting vessels.
New blood vessel formation by angiogenesis involves the degradation of extra-cellular …

Vascular endothelial growth factor and its receptors

G Neufeld, S Tessler, H Gitay-Goren, T Cohen… - Progress in growth factor …, 1994 - Elsevier
Vascular endothelial growth factor (VEGF) is a highly specific mitogen for vascular
endothelial cells and an angiogenic factor that is structurally related to platelet derived …

Vascular endothelial growth factor family of ligands and receptors

ZK Otrock, JA Makarem, AI Shamseddine - Blood Cells, Molecules, and …, 2007 - Elsevier
VEGF signaling often represents a critical rate-limiting step in physiological angiogenesis.
The VEGF family comprises seven secreted glycoproteins that are designated VEGF-A …

The role of VEGF receptors in angiogenesis; complex partnerships

S Cebe-Suarez, A Zehnder-Fjällman… - Cellular and molecular …, 2006 - Springer
Vascular endothelial growth factors (VEGFs) regulate blood and lymphatic vessel
development and homeostasis but also have profound effects on neural cells. VEGFs are …

Vascular endothelial growth factor: much more than an angiogenesis factor

DR Senger - Molecular biology of the cell, 2010 - Am Soc Cell Biol
Vascular endothelial growth factor (VEGF) is best known as a cytokine essential for
embryonic vasculogenesis and for the angiogenesis associated with various pathologies …

VEGF as a key mediator of angiogenesis in cancer

P Carmeliet - Oncology, 2005 - karger.com
Vascular endothelial growth factor (VEGF) is a homodimeric glycoprotein with a molecular
weight of approximately 45 kDa. It is the key mediator of angiogenesis (the formation of new …