Targeted nanocarriers for imaging and therapy of vascular inflammation

AM Chacko, ED Hood, BJ Zern… - Current opinion in colloid & …, 2011 - Elsevier
Vascular inflammation is a common, complex mechanism involved in pathogenesis of a
plethora of disease conditions including ischemia–reperfusion, atherosclerosis, restenosis …

Vascular targeting of nanoparticles for molecular imaging of diseased endothelium

PU Atukorale, G Covarrubias, L Bauer… - Advanced drug delivery …, 2017 - Elsevier
This review seeks to highlight the enormous potential of targeted nanoparticles for molecular
imaging applications. Being the closest point-of-contact, circulating nanoparticles can gain …

Applying nanomedicine in maladaptive inflammation and angiogenesis

A Alaarg, C Pérez-Medina, JM Metselaar… - Advanced drug delivery …, 2017 - Elsevier
Inflammation and angiogenesis drive the development and progression of multiple
devastating diseases such as atherosclerosis, cancer, rheumatoid arthritis, and inflammatory …

Employment of targeted nanoparticles for imaging of cellular processes in cardiovascular disease

M Modak, MA Frey, S Yi, Y Liu, EA Scott - Current opinion in biotechnology, 2020 - Elsevier
Cardiovascular disease (CVD) is a leading cause of global mortality, accounting for
pathologies that are primarily of atherosclerotic origin and driven by specific cell …

Engineering nanomaterials to address cell-mediated inflammation in atherosclerosis

S Allen, YG Liu, E Scott - Regenerative engineering and translational …, 2016 - Springer
Atherosclerosis is an inflammatory disorder with a pathophysiology driven by both innate
and adaptive immunity and a primary cause of cardiovascular disease (CVD) worldwide …

Multimodality nanotracers for cardiovascular applications

WJM Mulder, DP Cormode, S Hak… - Nature Clinical Practice …, 2008 - nature.com
Targeted imaging and therapeutics is becoming a field of prime importance in the study and
treatment of cardiovascular disease; it promises to enable early diagnosis, promote …

Targeting drug delivery in the vascular system: Focus on endothelium

PM Glassman, JW Myerson, LT Ferguson… - Advanced drug delivery …, 2020 - Elsevier
The bloodstream is the main transporting pathway for drug delivery systems (DDS) from the
site of administration to the intended site of action. In many cases, components of the …

Insights into atherosclerosis using nanotechnology

A Jayagopal, MRF Linton, S Fazio… - Current atherosclerosis …, 2010 - Springer
A developing forefront in vascular disease research is the application of nanotechnology,
the engineering of devices at the molecular scale, for diagnostic and therapeutic …

Current status of nanoparticle-based imaging agents for early diagnosis of cancer and atherosclerosis

G Saravanakumar, K Kim, JH Park… - Journal of …, 2009 - ingentaconnect.com
Endothelium plays a vital role in various vascular functions, and its dysfunction is a key
underlying process closely related to diverse array of diseases such as atherosclerosis and …

Nanocarriers for vascular delivery of anti-inflammatory agents

MD Howard, ED Hood, B Zern… - Annual review of …, 2014 - annualreviews.org
There is a need for improved treatment of acute vascular inflammation in conditions such as
ischemia-reperfusion injury, acute lung injury, sepsis, and stroke. The vascular endothelium …