Severe COVID-19 is a T cell immune dysregulatory disorder triggered by SARS-CoV-2
R Ameratunga, ST Woon, R Steele… - Expert Review of …, 2022 - Taylor & Francis
Introduction COVID-19 has had a calamitous impact on the global community. Apart from at
least 6 M deaths, hundreds of millions have been infected and a much greater number have …
least 6 M deaths, hundreds of millions have been infected and a much greater number have …
Prevention and treatment of COVID‐19 disease by controlled modulation of innate immunity
V Schijns, EC Lavelle - European journal of immunology, 2020 - Wiley Online Library
The recent outbreak of coronavirus disease 2019 (COVID‐19), triggered by the severe acute
respiratory syndrome coronavirus 2 (SARS‐CoV‐2) poses an enormous threat to global …
respiratory syndrome coronavirus 2 (SARS‐CoV‐2) poses an enormous threat to global …
The immune system as a target for therapy of SARS-CoV-2: a systematic review of the current immunotherapies for COVID-19
AH Mansourabadi, M Sadeghalvad… - Life sciences, 2020 - Elsevier
Aims The immune response is essential for the control and resolution of viral infections.
Following the outbreak of novel coronavirus disease (COVID-19), several immunotherapies …
Following the outbreak of novel coronavirus disease (COVID-19), several immunotherapies …
Deciphering the COVID‐19 cytokine storm: systematic review and meta‐analysis
R Mulchandani, T Lyngdoh… - European journal of …, 2021 - Wiley Online Library
Introduction The coronavirus pandemic has affected more than 20 million people so far.
Elevated cytokines and suppressed immune responses have been hypothesized to set off a …
Elevated cytokines and suppressed immune responses have been hypothesized to set off a …
Humoral immune mechanisms involved in protective and pathological immunity during COVID-19
G Widjaja, AT Jalil, HS Rahman, WK Abdelbasset… - Human Immunology, 2021 - Elsevier
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causing COVID-19 is
associated with excessive inflammation, as a main reason for severe condition and death …
associated with excessive inflammation, as a main reason for severe condition and death …
[HTML][HTML] Characterisation of the pro-inflammatory cytokine signature in severe COVID-19
Clinical outcomes from infection with SARS-CoV-2, the cause of the COVID-19 pandemic,
are remarkably variable ranging from asymptomatic infection to severe pneumonia and …
are remarkably variable ranging from asymptomatic infection to severe pneumonia and …
[HTML][HTML] COVID-19: The emerging immunopathological determinants for recovery or death
Hyperactivation of the host immune system during infection by SARS-CoV-2 is the leading
cause of death in COVID-19 patients. It is also evident that patients who develop …
cause of death in COVID-19 patients. It is also evident that patients who develop …
[HTML][HTML] Cytokine storm in COVID-19—immunopathological mechanisms, clinical considerations, and therapeutic approaches: the REPROGRAM consortium position …
Cytokine storm is an acute hyperinflammatory response that may be responsible for critical
illness in many conditions including viral infections, cancer, sepsis, and multi-organ failure …
illness in many conditions including viral infections, cancer, sepsis, and multi-organ failure …
Complexity of immune responses in COVID-19
The global COVID-19 pandemic has caused substantial morbidity and mortality to humanity.
Remarkable progress has been made in understanding both the innate and adaptive …
Remarkable progress has been made in understanding both the innate and adaptive …
Coronavirus disease 2019 (COVID-19): Immunological approaches and emerging pharmacologic treatments
P Goodarzi, F Mahdavi, R Mirzaei, H Hasanvand… - International …, 2020 - Elsevier
The SARS-CoV-2 virus is an etiological agent of pandemic COVID-19, which spreads
rapidly worldwide. No proven effective therapies currently exist for this virus, and efforts to …
rapidly worldwide. No proven effective therapies currently exist for this virus, and efforts to …