Designer cellulosomes (DCs) are engineered multi-enzyme complexes, comprising
carbohydrate-active enzymes attached to a common backbone, the scaffoldin, via high …

Cellulose, a primary component of lignocellulosic biomass, is the most abundant
carbohydrate polymer in nature. Only a limited number of microorganisms are known to …

Background Natural cellulosome multi-enzyme complexes, their components, and
engineered 'designer cellulosomes'(DCs) promise an efficient means of breaking down …

Degradation of cellulose is of major interest in the quest for alternative sources of renewable
energy, for its positive effects on environment and ecology, and for use in advanced …

Cellulosomes are multi-enzymatic nanomachines that have been fine-tuned through
evolution to efficiently deconstruct plant biomass. Integration of cellulosomal components …

Background Designer cellulosomes are self-assembled chimeric enzyme complexes that
can be used to improve lignocellulosic biomass degradation. They are composed of a …

Background Select cellulolytic bacteria produce multi-enzymatic cellulosome complexes that
bind to the plant cell wall and catalyze its efficient degradation. The multi-modular …

During the past several years, major progress has been accomplished in the production of
“designer cellulosomes,” artificial enzymatic complexes that were demonstrated to efficiently …

In this study, novel cellulosome chimeras exhibiting atypical geometries and binding modes,
wherein the targeting and proximity functions were directly incorporated as integral parts of …

Cellulosomes are synthesized by anaerobic bacteria and fungi to degrade lignocellulose via
synergistic action of multiple enzymes fused to a protein scaffold. Through templating key …