Antibiotic resistance continues to evolve and spread beyond all boundaries, resulting in an
increase in morbidity and mortality for non-curable infectious diseases. Due to the failure of …

Antimicrobial resistance threatens a resurgence of life-threatening bacterial infections and
the potential demise of many aspects of modern medicine. Despite intensive drug discovery …

Summary Antibiotic Resistance in Gram‐negative bacteria remains one of the most pressing
global health challenges. Our inability to discover novel antibacterial agents against Gram …

Antibiotic resistance has progressed in recent years from a field of investigation for
researchers, and a problem for physicians and their hospitalized patients, to one of the most …

Bacteria are increasingly developing resistance against the antibiotics of last resort, which
has created enormous threats in the face of global public health. In order to address this …

An increasing number of bacterial pathogens are acquiring resistance to the commonly used
antibiotics. This has spurred a global threat leading to a resistance era and has penetrated …

The need for new antibiotics to effectively treat antibiotic-resistant infections remains
unfulfilled. Despite the well-publicised concern over this issue, only two novel antibiotic …

Overall, the articles in this Research Topic highlight a spectrum of research encompassing
the importance of pursuing work to explore new ways of treating multidrug resistant bacteria …

Bacterial resistance has become increasingly serious because of the widespread use and
abuse of antibiotics. In particular, the emergence of multidrug-resistant bacteria has posed a …

Multidrug-resistant (MDR) bacterial infections, especially those caused by Gram-negative
pathogens, have emerged to be one of the world's greatest health threats. However, not only …