RNA splicing control: yet another gene regulatory role for long nuclear noncoding RNAs

X Zong, V Tripathi, KV Prasanth - RNA biology, 2011 - Taylor & Francis
The mammalian genome harbors a large number of long non-coding RNAs (lncRNAs) that
do not code for proteins, but rather they exert their function directly as RNA molecules …

Long non-coding RNAs and splicing

D Staněk - Essays in biochemistry, 2021 - portlandpress.com
In this review I focus on the role of splicing in long non-coding RNA (lncRNA) life. First, I
summarize differences between the splicing efficiency of protein-coding genes and lncRNAs …

Splicing regulation by long noncoding RNAs

N Romero-Barrios, MF Legascue… - Nucleic acids …, 2018 - academic.oup.com
Massive high-throughput sequencing techniques allowed the identification of thousands of
noncoding RNAs (ncRNAs) and a plethora of different mRNA processing events occurring in …

[PDF][PDF] Diverse functions of nuclear non-coding RNAs in eukaryotic gene expression

M Chinen, T Tani - Front. Biosci, 2012 - article.imrpress.com
Introduction 3. NcRNA-mediated regulation of transcription 3.1. Direct modulation of
transcription factors 3.2. Promoter interference 4. Epigenetic gene silencing directed by …

Exploring the alternative splicing of long noncoding RNAs

MR Khan, RJ Wellinger, B Laurent - Trends in Genetics, 2021 - cell.com
Like protein-coding genes, long noncoding RNA (lncRNA) genes are composed of introns
and exons. After their transcription, lncRNAs are subject to constitutive and/or alternative …

[HTML][HTML] Emerging roles of lncRNAs in the post-transcriptional regulation in cancer

RZ He, DX Luo, YY Mo - Genes & diseases, 2019 - Elsevier
Accumulating evidence indicates that long non-coding RNAs (lncRNAs) can play a pivotal
role in regulation of diverse cellular processes. In particular, lncRNAs can serve as master …

[HTML][HTML] The nuclear functions of long noncoding RNAs come into focus

Z Song, J Lin, Z Li, C Huang - Non-coding RNA Research, 2021 - Elsevier
Long noncoding RNAs (lncRNAs), defined as untranslated and tightly-regulated transcripts
with a length exceeding 200 nt, are common outputs of the eukaryotic genome. It is …

Functional insights into the role of nuclear-retained long noncoding RNAs in gene expression control in mammalian cells

DK Singh, KV Prasanth - Chromosome research, 2013 - Springer
The mammalian genome harbors thousands of long noncoding RNA (lncRNA) genes.
Recent studies have indicated the involvement of several of these lncRNAs in the regulation …

Regulation of alternative splicing by short non-coding nuclear RNAs

A Khanna, S Stamm - RNA biology, 2010 - Taylor & Francis
Recent results from deep-sequencing and tiling array studies indicated the existence of a
large number of short, metabolically stable, non-coding RNAs. Some of these short RNAs …

Intronic RNA: Ad 'junk'mediator of post-transcriptional gene regulation

CR Neil, WG Fairbrother - Biochimica et Biophysica Acta (BBA)-Gene …, 2019 - Elsevier
RNA splicing, the process through which intervening segments of noncoding RNA (introns)
are excised from pre-mRNAs to allow for the formation of a mature mRNA product, has long …