Targeted metabolomics identifies high performing diagnostic and prognostic biomarkers for COVID-19

Y López-Hernández, J Monárrez-Espino… - Scientific Reports, 2021 - nature.com
Research exploring the development and outcome of COVID-19 infections has led to the
need to find better diagnostic and prognostic biomarkers. This cross-sectional study used …

Untargeted metabolomics of COVID-19 patient serum reveals potential prognostic markers of both severity and outcome

I Roberts, M Wright Muelas, JM Taylor, AS Davison… - Metabolomics, 2022 - Springer
Introduction The diagnosis of COVID-19 is normally based on the qualitative detection of
viral nucleic acid sequences. Properties of the host response are not measured but are key …

Longitudinal metabolomics of human plasma reveals prognostic markers of COVID-19 disease severity

M Sindelar, E Stancliffe, M Schwaiger-Haber… - Cell Reports …, 2021 - cell.com
There is an urgent need to identify which COVID-19 patients will develop life-threatening
illness so that medical resources can be optimally allocated and rapid treatment can be …

MetaboliteCOVID: A manually curated database of metabolite markers for COVID-19

L Ren, L Ning, Y Yang, T Yang, X Li, S Tan, P Ge… - Computers in Biology …, 2023 - Elsevier
In the realm of unraveling COVID-19's intricacies, numerous metabolomic investigations
have been conducted to discern the unique metabolic traits exhibited within infected …

Meta-analysis of COVID-19 metabolomics identifies variations in robustness of biomarkers

A Onoja, J Von Gerichten, HM Lewis, MJ Bailey… - International journal of …, 2023 - mdpi.com
The global COVID-19 pandemic resulted in widespread harms but also rapid advances in
vaccine development, diagnostic testing, and treatment. As the disease moves to endemic …

Combining semi-targeted metabolomics and machine learning to identify metabolic alterations in the serum and urine of hospitalized patients with COVID-19

G Baiges-Gaya, S Iftimie, H Castañé… - Biomolecules, 2023 - mdpi.com
Viral infections cause metabolic dysregulation in the infected organism. The present study
used metabolomics techniques and machine learning algorithms to retrospectively analyze …

Metabolomics markers of COVID-19 are dependent on collection wave

HM Lewis, Y Liu, CF Frampas, K Longman, M Spick… - Metabolites, 2022 - mdpi.com
The effect of COVID-19 infection on the human metabolome has been widely reported, but to
date all such studies have focused on a single wave of infection. COVID-19 has generated …

Metabolic signatures associated with severity in hospitalized COVID-19 patients

J Marín-Corral, J Rodríguez-Morató… - International journal of …, 2021 - mdpi.com
The clinical evolution of COVID-19 pneumonia is poorly understood. Identifying the
metabolic pathways that are altered early with viral infection and their association with …

Comprehensive meta-analysis of COVID-19 global metabolomics datasets

Z Pang, G Zhou, J Chong, J Xia - Metabolites, 2021 - mdpi.com
The novel coronavirus SARS-CoV-2 has spread across the world since 2019, causing a
global pandemic. The pathogenesis of the viral infection and the associated clinical …

Biological and clinical factors contributing to the metabolic heterogeneity of hospitalized patients with and without COVID-19

A D'alessandro, T Thomas, IJ Akpan, JA Reisz… - Cells, 2021 - mdpi.com
The Corona Virus Disease 2019 (COVID-19) pandemic represents an ongoing worldwide
challenge. The present large study sought to understand independent and overlapping …