Background Neuropathy often occurs following drug treatment such as chemotherapy.
Severe instances of neuropathy can result in cessation of life-saving chemotherapy …

Abstract Background Drug adverse events (AEs), or called adverse drug events (ADEs), are
ranked one of the leading causes of mortality. The Ontology of Adverse Events (OAE) has …

Abstract Background Adverse drug reactions (ADRs), also called as drug adverse events
(AEs), are reported in the FDA drug labels; however, it is a big challenge to properly retrieve …

Drug-drug interactions form a significant risk group for adverse effects associated with
pharmaceutical treatment. These interactions are often reported in the literature, however …

The growing significance of bioinformatics and systems biology in drug safety research
requires a system of adverse‐event classification that goes beyond a simple vocabulary …

Background Drug ontologies could help pharmaceutical researchers overcome information
overload and speed the pace of drug discovery, thus benefiting the industry and patients …

Introduction A translational bioinformatics challenge exists in connecting population and
individual clinical phenotypes in various formats to biological mechanisms. The Medical …

OBJECTIVE: The purpose of this study was to integrate knowledge about drugs, drug
targets, and topological methods. The goals were to build a system facilitating the study of …

Compared with controlled terminologies (eg, MedDRA, CTCAE, and WHO-ART), the
community-based Ontology of Adverse Events (OAEs) has many advantages in AE …

Abstract Background The Adverse Event Reporting System (AERS) is an FDA database
providing rich information on voluntary reports of adverse drug events (ADEs). Normalizing …