Over the past 70 years, a number of astute clinicians in the field of dental medicine have
observed and recorded the relationship between periodontopathies and systemic …

The approach to the diagnosis and treatment of periodontal disease is changing. The
disease has not changed, but dentistry's understanding of the pathogenesis and …

A bstract Recent evidence indicates that we need to change how we think about the etiology
and pathogenesis of periodontal disease. Although bacteria are a necessary factor in the …

Periodontitis is now seen as resulting from a complex interplay of bacterial infection and host
response, often modified by behavioral factors. There has been a fundamental change in the …

Severe periodontitis is defined by extensive loss of the tooth attachment apparatus. It is the
sixth most common human disease and is estimated to affect 11.2% of the global adult …

The effects and consequences of periodontal diseases might not be confined to the oral
cavity. A great body of evidence has arisen supporting the claim demonstrating an …

Major advances have been made in our basic understanding of periodontal disease during
the last decade. Pathways whereby bacteria destroy the periodontal connective tissues and …

The possibility that a localized oral condition such as periodontal disease (PD) may have
systemic effects seems to be of interest to the average person. The notion that a condition …

The purpose of this volume of PERIODONTOLOGY 2000 is to present the basic concepts
and facts constituting the current understanding of the pathogenesis of human periodontitis …

The pathogenesis of human periodontitis was placed on a rational footing for the first time by
Page & Schroeder in 1976 (7). Although the details were scanty, the general principles and …