Neuroinflammatory microenvironment, regulating neurite regrowth and neuronal survival,
plays a critical role in Alzheimer's disease (AD). During neuroinflammation, microglia are …

Alzheimer's disease (AD) is a common neurodegenerative disease associated with
deposition of β-amyloid peptide (Aβ). Platycodin D (PLD), a triterpenesaponin, may possess …

abstract Neurodegenerative diseases (NDs) are characterized by the progressive loss of
structure and function of neurons most common in elderly population, mainly including …

Ethnopharmacological relevance Alzheimer's disease (AD) was considered to be a
neurodegenerative disease that caused cognitive impairment. Reactive Oxidative stress …

Alzheimer's disease (AD) is a neurodegenerative disorder that has quickly becoming one of
the most expensive, lethal, and burdening diseases of this century. In the past twenty years …

In response to the microenvironment, microglia may polarize into either an M1 pro-
inflammatory phenotype, exacerbating neurotoxicity, or an M2 anti-inflammatory phenotype …

Emerging evidence suggests the regulation of microglial phenotype balance between M1
and M2 will be a potential therapeutic strategy for microglia-mediated neuroinflammation in …

Alzheimer's disease (AD) is the most common cause of dementia in the elderly. Although its
pathogenesis remains unclear, studies have indicated microglia-mediated …

Neuroinflammation is considered to be an important and inevitable pathological process
associated with all types of damages to, and disorders of, the central nervous system. The …

Alzheimer's disease (AD) has become the most prevalent neurodegenerative disorder.
Given the pathogenesis of AD is unclear, there is currently no drug approved to halt or delay …