Peripheral blood dendritic cells reinduce proliferation in in vitro aged T cell populations

MM Steger, C Maczek… - Mechanisms of ageing and …, 1997 - Elsevier
Dendritic cells (DC) are professional antigen presenting cells which are essential for the
initiation of an immune response. Recently we demonstrated that DC, which had been …

Unimpaired dendritic cells can be derived from monocytes in old age and can mobilize residual function in senescent T cells

TL Lung, M Saurwein-Teissl, W Parson, D Schönitzer… - Vaccine, 2000 - Elsevier
Dendritic cells (DC) are powerful antigen presenting cells, which have the unique capacity to
stimulate naive T cells. In spite of the well-known decline of T cell function in old age, little …

Morphologically and functionally intact dendritic cells can be derived from the peripheral blood of aged individuals

MM Steger, C Maczek… - Clinical & …, 1996 - Wiley Online Library
Dendritic cells are antigen‐presenting cells (APC), which are crucial for the initiation of an
immune response. In spite of the well known decline of immune function in old age, no …

Dendritic cells in old age-neglected by gerontology?

M Saurwein-Teissl, N Romani… - Mechanisms of ageing …, 2001 - Elsevier
Dendritic cells (DC) are known as the most efficient antigen-presenting cell type to activate T
cells and are key modulators of the immune response. Due to their central role in …

Ageing impairs the T cell response to dendritic cells

J You, H Dong, ER Mann, SC Knight, P Yaqoob - Immunobiology, 2013 - Elsevier
Dendritic cells (DCs) are critical in priming adaptive T-cell responses, but the effects of
ageing on interactions between DCs and T cells are unclear. This study investigated the …

Phenotype and functions of conventional dendritic cells are not compromised in aged mice

SY Tan, LL Cavanagh, W d'Advigor… - Immunology and cell …, 2012 - Wiley Online Library
Aging has profound effects on the immune system, including thymic involution, reduced
diversity of the T cell receptor repertoire, reduced effector T cell and B cell function and …

Peripheral blood dendritic cells and monocytes are differently regulated in the elderly

S Della Bella, L Bierti, P Presicce, R Arienti, M Valenti… - Clinical …, 2007 - Elsevier
Dendritic cells (DCs) are the single most central player in all immune responses. To assess
whether DC alterations may contribute to the immune dysregulation that affects the elderly …

Dendritic cells in human aging

A Agrawal, S Agrawal, S Gupta - Experimental gerontology, 2007 - Elsevier
Dendritic cells (DCs) play a critical role in linking innate and adaptive immunity. A role of
DCs in immunosenescence and chronic inflammation associated with aging has not been …

Antigen receptors and dendritic cells

S Lebecque - Vaccine, 2000 - Elsevier
Several age-related alterations occurring in the immune system, especially in T cells and in
B cells, may account for an increased susceptibility to infections, autoimmune diseases, and …

Role of dendritic cells in innate and adaptive immune response in human aging

S Gupta - Experimental gerontology, 2014 - Elsevier
Aging is associated with a progressive decline in T cell function, chronic inflammation,
hyperimmunoglobulinemia, autoimmunity, poor response to vaccines, and increased …